Determinants of depression in patients with comorbid depression following cardiac rehabilitation

TY - JOUR

T1 - Determinants of depression in patients with comorbid depression following cardiac rehabilitation

AU - Sever, Serdar

AU - Harrison, Alexander Stephen

AU - Golder, Susan Pamela

AU - Doherty, Patrick Joseph

N1 - © Author(s) (or their employer(s))

PY - 2019/4/9

Y1 - 2019/4/9

N2 - Background A prior history of depression, at the pointpatients start cardiac rehabilitation (CR), is associatedwith poor outcomes; however, little is known about whichfactors play a part in determining the extent of benefitfollowing CR. Therefore, we aim to identify and evaluatedeterminants of CR depression outcomes in patients withcomorbid depression.Methods An observational study of routine practice usingthe British Heart Foundation National Audit of CardiacRehabilitation data between April 2012 and March 2017.Baseline characteristics were examined with independentsamples t-test and χ2 test. A binary logistic regression wasused to predict change in depression outcome followingCR.Results The analysis included 2715 CR participants withdepression history. The determinants of Hospital Anxietyand Depression Scale (HADS) depression measurementpost-CR were higher total number of comorbidities (OR0.914, 95%CI 0.854 to 0.979), a higher HADS anxietyscore (OR 0.883, 95%CI 0.851 to 0.917), physicalinactivity (OR 0.707, 95%CI 0.514 to 0.971), not-smokingat baseline (OR 1.774, 95%CI 1.086 to 2.898) and malegender (OR 0.721, 95%CI 0.523 to 0.992).Conclusion Baseline characteristics of patients withcomorbid depression such as higher anxiety, higher totalnumber of comorbidities, smoking, physical inactivityand male gender were predictors of their depressionlevels following CR. CR programmes need to be awareof comorbid depression and these related patientcharacteristics associated with better CR outcomes.

AB - Background A prior history of depression, at the pointpatients start cardiac rehabilitation (CR), is associatedwith poor outcomes; however, little is known about whichfactors play a part in determining the extent of benefitfollowing CR. Therefore, we aim to identify and evaluatedeterminants of CR depression outcomes in patients withcomorbid depression.Methods An observational study of routine practice usingthe British Heart Foundation National Audit of CardiacRehabilitation data between April 2012 and March 2017.Baseline characteristics were examined with independentsamples t-test and χ2 test. A binary logistic regression wasused to predict change in depression outcome followingCR.Results The analysis included 2715 CR participants withdepression history. The determinants of Hospital Anxietyand Depression Scale (HADS) depression measurementpost-CR were higher total number of comorbidities (OR0.914, 95%CI 0.854 to 0.979), a higher HADS anxietyscore (OR 0.883, 95%CI 0.851 to 0.917), physicalinactivity (OR 0.707, 95%CI 0.514 to 0.971), not-smokingat baseline (OR 1.774, 95%CI 1.086 to 2.898) and malegender (OR 0.721, 95%CI 0.523 to 0.992).Conclusion Baseline characteristics of patients withcomorbid depression such as higher anxiety, higher totalnumber of comorbidities, smoking, physical inactivityand male gender were predictors of their depressionlevels following CR. CR programmes need to be awareof comorbid depression and these related patientcharacteristics associated with better CR outcomes.

U2 - 10.1136/ openhrt-2018-000973

DO - 10.1136/ openhrt-2018-000973

M3 - Article

SN - 2053-3624

VL - 6

JO - Open Heart

JF - Open Heart

IS - 1

ER -