@article{882a825e5f60413e91b3ef1322eca00c,
title = "Development of pharmaceutically relevant bio-based intermediates though aldol condensation and Claisen-Schmidt reactions of dihydrolevoglucosenone (Cyrene{\textregistered})",
abstract = "Dihydrolevoglucosenone (Cyrene{\textregistered}) has been successfully utilised as a bio-based platform molecule for the synthesis of pharmaceutically relevant intermediates through aldol condensation reactions. Utilising sustainable synthetic methodologies, the self-aldol condensations reaction of Cyrene was achieved in high purity, with isolated yields of 81.3%. Claisen-Schmidt reactions with a range of aromatic and heteroaromatic aldehydes yielded novel cyrene-based compounds, characterised by single-crystal X-ray diffraction, FT-IR, NMR and MS.",
author = "Liam Hughes and McElroy, {Con Robert} and Whitwood, {Adrian C.} and Andrew Hunt",
note = " {\textcopyright} The Royal Society of Chemistry 2018. This is an author-produced version of the published paper. Uploaded in accordance with the publisher{\textquoteright}s self-archiving policy. Further copying may not be permitted; contact the publisher for details",
year = "2018",
month = may,
day = "25",
doi = "10.1039/C8GC01227J",
language = "English",
pages = "1--6",
journal = "Green Chemistry",
issn = "1463-9270",
publisher = "The Royal Society of Chemistry",
}