The York Research Database

Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice

McNae, I. W., Kinkead, J., Malik, D., Yen, L-H., Walker, M. K., Swain, C., Webster, S. P., Gray, N., Fernandes, P. M., Myburgh, E., Blackburn, E. A., Ritchie, R., Austin, C., Wear, M. A., Highton, A. J., Keats, A. J., Vong, A., Dornan, J., Mottram, J. C., Michels, P. A. M. & 2 others, Pettit, S. & Walkinshaw, M. D., 16 Feb 2021

Article in Nature Communications

Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors

Saldivia Concepcion, M. A., Fang, E., Ma, X., Myburgh, E., Brambilla Carnielli Trindade, J., Bower-Lepts, C., Brown, E., Ritchie, R., Lakshminarayana, S. B., Chen, Y-L., Patra, D., Ornelas, E., Koh, H. X. Y., Williams, S., Supek, F., Paape, D., McCulloch, R., Kaiser, M., Barrett, M. P., Jiricek, J. & 3 others, Diagana, T. T., Mottram, J. C. & Rao, S. P. S., Oct 2020

Article in Nature Microbiology

Anti-Trypanosomal Proteasome Inhibitors Cure Hemolymphatic and Meningoencephalic Murine Infection Models of African Trypanosomiasis

Rao, S. P. S., Lakshminarayana, S. B., Jiricek, J., Kaiser, M., Ritchie, R., Myburgh, E., Supek, F., Tuntland, T., Nagle, A., Molteni, V., Mäser, P., Mottram, J. C., Barrett, M. P. & Diagana, T. T., 17 Feb 2020

Article in Tropical medicine and infectious disease

In Vivo Bioluminescence Imaging to Assess Compound Efficacy Against Trypanosoma brucei

Ritchie, R., Barrett, M. P., Mottram, J. C. & Myburgh, E., 2020

Article in Methods in Molecular Biology

TLR2 signaling in skin non-hematopoietic cells induces early neutrophil recruitment in response to Leishmania major infection

Ronet, C., Passelli, K., Charmoy, M., Scarpellino, L., Myburgh, E., Hauyon La Torre, Y., Turco, S., Mottram, J. C., Fasel, N., Luther, S. A., Beverley, S. M., Launois, P. & Tacchini-Cottier, F., 27 Dec 2018

Article in Journal of investigative dermatology