Dihydrolevoglucosenone (Cyrene) as a bio-based alternative for dipolar aprotic solvents

James Sherwood, Mario De Bruyn, Andri Constantinou, Laurianne Moity, Rob McElroy, Thomas J. Farmer, Tony Duncan, Warwick Raverty, Andrew J. Hunt, James H. Clark*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Dihydrolevoglucosenone (Cyrene) is a bio-based molecule, derived in two simple steps from cellulose, which demonstrates significant promise as a dipolar aprotic solvent. The dipolarity of dihydrolevoglucosenone is similar to NMP, DMF and sulpholane. Dihydrolevoglucosenone demonstrates similar performance to NMP in a fluorination reaction and the Menschutkin reaction. This journal is © the Partner Organisations 2014.

Original languageEnglish
Pages (from-to)9650-9652
Number of pages3
JournalChemical Communications
Issue number68
Early online date1 Jul 2014
Publication statusPublished - 4 Sept 2014

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