TY - JOUR
T1 - Disorders of representation and control in semantic cognition
T2 - Effects of familiarity, typicality, and specificity
AU - Rogers, Timothy T.
AU - Patterson, Karalyn
AU - Jefferies, Elizabeth
AU - Lambon Ralph, Matthew A.
N1 - © 2015, The Authors.
PY - 2015/9/1
Y1 - 2015/9/1
N2 - We present a case-series comparison of patients with cross-modal semantic impairments consequent on either (a) bilateral anterior temporal lobe atrophy in semantic dementia (SD) or (b) left-hemisphere fronto-parietal and/or posterior temporal stroke in semantic aphasia (SA). Both groups were assessed on a new test battery designed to measure how performance is influenced by concept familiarity, typicality and specificity. In line with previous findings, performance in SD was strongly modulated by all of these factors, with better performance for more familiar items (regardless of typicality), for more typical items (regardless of familiarity) and for tasks that did not require very specific classification, consistent with the gradual degradation of conceptual knowledge in SD. The SA group showed significant impairments on all tasks but their sensitivity to familiarity, typicality and specificity was more variable and governed by task-specific effects of these factors on controlled semantic processing. The results are discussed with reference to theories about the complementary roles of representation and manipulation of semantic knowledge.
AB - We present a case-series comparison of patients with cross-modal semantic impairments consequent on either (a) bilateral anterior temporal lobe atrophy in semantic dementia (SD) or (b) left-hemisphere fronto-parietal and/or posterior temporal stroke in semantic aphasia (SA). Both groups were assessed on a new test battery designed to measure how performance is influenced by concept familiarity, typicality and specificity. In line with previous findings, performance in SD was strongly modulated by all of these factors, with better performance for more familiar items (regardless of typicality), for more typical items (regardless of familiarity) and for tasks that did not require very specific classification, consistent with the gradual degradation of conceptual knowledge in SD. The SA group showed significant impairments on all tasks but their sensitivity to familiarity, typicality and specificity was more variable and governed by task-specific effects of these factors on controlled semantic processing. The results are discussed with reference to theories about the complementary roles of representation and manipulation of semantic knowledge.
UR - http://www.scopus.com/inward/record.url?scp=84944065563&partnerID=8YFLogxK
U2 - 10.1016/j.neuropsychologia.2015.04.015
DO - 10.1016/j.neuropsychologia.2015.04.015
M3 - Article
AN - SCOPUS:84944065563
SN - 0028-3932
VL - 76
SP - 220
EP - 239
JO - Neuropsychologia
JF - Neuropsychologia
ER -