Abstract
This study measured the correlation between the strength of a Gist signal and case difficulty
based on standard presentation and reporting mechanisms for 80 cases. Half of the cases contained
biopsy-proven cancer while the remainder were normal and confirmed to be cancer-free for at least two
years of follow-up. In the Gist experiment, seventeen breast radiologists and physicians gave an
abnormality score on a scale from 0 (confident normal) to 100 (confident abnormal) to unilateral CC
mammograms following a very brief, 500 millisecond presentation of the image. Independently, each
mammogram was assessed by a separate sample of at least 40 radiologists using standard
presentation and reporting mechanisms, with these readers asked to locate any cancers present. All
readers reported at least 1000 cases annually. For each case and each category, the percentage of
correct reports served as an objective measure of case difficulty. For each of the 17 readers, the
association between the abnormality scores from the gist study and detection rates from the earlier
reports was examined using Spearman correlation. None of the coefficients were significantly different
from zero (p>0.05). For the normal cases, the correlation coefficient between abnormality scores and
detection rates for the 17 readers ranged from -0.262 to 0.258, and for cancer -0.180 to 0.309. The
results suggest that the gist signal may indicate the presence of cancer, using mechanisms other than
those employed in usual reporting, and might be exploited to improve breast cancer detection.
Original language | English |
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Title of host publication | Proc. SPIE 10952, Medical Imaging 2019 |
Subtitle of host publication | Image Perception, Observer Performance, and Technology Assessment, 1095203 |
Editors | Robert M. Nishikawa, Frank W. Samuelson |
Publisher | SPIE |
Volume | 10952 |
DOIs | |
Publication status | Published - 4 Mar 2019 |
Event | Medical Imaging 2019: Image Perception, Observer Performance, and Technology Assessment - San Diego, United States Duration: 20 Feb 2019 → 21 Feb 2019 |
Publication series
Name | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
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Volume | 10952 |
ISSN (Print) | 1605-7422 |
Conference
Conference | Medical Imaging 2019: Image Perception, Observer Performance, and Technology Assessment |
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Country/Territory | United States |
City | San Diego |
Period | 20/02/19 → 21/02/19 |
Bibliographical note
Publisher Copyright:© 2019 SPIE.
Keywords
- Breast cancer
- Breast cancer risk
- GIST
- Mammography
- Prior mammograms