ECONOMIC-ANALYSIS ALONGSIDE CLINICAL-TRIALS - PROBLEMS AND POTENTIAL

M Drummond

ECONOMIC-ANALYSIS ALONGSIDE CLINICAL-TRIALS - PROBLEMS AND POTENTIAL

Centre for Health Economics

Research output: Contribution to journal › Article › peer-review

Abstract

Controlled clinical trials are recognized as the best source of data on the efficacy of health care interventions. Because economic evaluation is dependent on the quality of the underlying medical evidence, clinical trials have increasingly been viewed as the natural vehicle for economic analysis. However, the closer integration of economic and clinical research raises many methodological issues. This paper discusses these issues in trial design, collection of resource use and outcome data, and the interpretation of results. Suggestions are made for resolving the major problems.

Original language	English
Pages (from-to)	1403-1407
Number of pages	5
Journal	The Journal of Rheumatology
Volume	22
Issue number	7
Publication status	Published - Jul 1995

Keywords

COST-BENEFIT ANALYSIS
CLINICAL TRIALS
OUTCOME ASSESSMENT
COST-EFFECTIVENESS
PROPHYLAXIS

Cite this

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title = "ECONOMIC-ANALYSIS ALONGSIDE CLINICAL-TRIALS - PROBLEMS AND POTENTIAL",

abstract = "Controlled clinical trials are recognized as the best source of data on the efficacy of health care interventions. Because economic evaluation is dependent on the quality of the underlying medical evidence, clinical trials have increasingly been viewed as the natural vehicle for economic analysis. However, the closer integration of economic and clinical research raises many methodological issues. This paper discusses these issues in trial design, collection of resource use and outcome data, and the interpretation of results. Suggestions are made for resolving the major problems.",

keywords = "COST-BENEFIT ANALYSIS, CLINICAL TRIALS, OUTCOME ASSESSMENT, COST-EFFECTIVENESS, PROPHYLAXIS",

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AB - Controlled clinical trials are recognized as the best source of data on the efficacy of health care interventions. Because economic evaluation is dependent on the quality of the underlying medical evidence, clinical trials have increasingly been viewed as the natural vehicle for economic analysis. However, the closer integration of economic and clinical research raises many methodological issues. This paper discusses these issues in trial design, collection of resource use and outcome data, and the interpretation of results. Suggestions are made for resolving the major problems.

KW - COST-BENEFIT ANALYSIS

KW - CLINICAL TRIALS

KW - OUTCOME ASSESSMENT

KW - COST-EFFECTIVENESS

KW - PROPHYLAXIS

M3 - Article

SN - 0315-162X

VL - 22

SP - 1403

EP - 1407

JO - The Journal of Rheumatology

JF - The Journal of Rheumatology

IS - 7

ER -