Economic analysis of VenUS I, a randomized trial of two bandages for treating venous leg ulcers

C P Iglesias, E A Nelson, N Cullum, D J Torgerson, VenUS I Collaborators

Research output: Contribution to journalArticlepeer-review


Background: The study investigated the cost-effectiveness of four-layer and short-stretch compression bandages for treating venous leg ulcers. Methods: Cost-effectiveness and cost-utility analyses were performed using patient-level data collected alongside the VenUS I leg ulcer study. The perspective for the economic analysis was that of the UK National Health Service (NHS) and Personal Social Service. The time horizon for the analysis was 1 year after recruitment. Health benefit was measured as differences in ulcer-free days and quality-adjusted life years (QALYs).

Results; The mean healing time for ulcers treated with four-layer bandages was 10.9 (95 percent confidence interval (c.i.) -6-8 to 29.1) days less than that for ulcers treated with short-stretch bandages. Mean average difference in QALYs between compression systems was -0.02 (95 per cent c.i. -0.08 to 0.04). The four-layer bandage cost a mean of pound227.32 (95 per cent c.i. pound16.53 to pound448.30) less per patient per year than the short-stretch bandage.

Conclusion: On average, four-layer bandaging was associated with greater health benefits and lower costs than short-stretch bandaging.

Original languageEnglish
Pages (from-to)1300-1306
Number of pages7
JournalBritish Journal of Surgery
Issue number10
Publication statusPublished - Oct 2004



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