Effect of age, sex and morbidity count on trial attrition: meta-analysis of individual participant-level data from phase 3/4 industry-funded clinical trials

Jennifer S Lees; Peter Hanlon; Elaine Butterly; Sarah H. Wild; Frances S Mair; Rod S Taylor; Bruce Guthrie; Katie Gillies; Sofia Dias; Nicky J. Welton; David A. McAllister

doi:10.1136/bmjmed-2022-000217

Effect of age, sex and morbidity count on trial attrition: meta-analysis of individual participant-level data from phase 3/4 industry-funded clinical trials

Jennifer S Lees, Peter Hanlon, Elaine Butterly, Sarah H. Wild, Frances S Mair, Rod S Taylor, Bruce Guthrie, Katie Gillies, Sofia Dias, Nicky J. Welton, David A. McAllister

Centre for Reviews and Dissemination

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	e000217
Number of pages	11
Journal	BMJ Medicine
Volume	1
DOIs	https://doi.org/10.1136/bmjmed-2022-000217
Publication status	Published - 1 Sept 2022

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10.1136/bmjmed-2022-000217Licence: CC BY

Effect of age, sex, and morbidity count on trial attrition: metaanalysis of individual participant level data from phase 3/4 industry funded clinical trials
© Author(s) (or their employer(s)) 2022.
Final published version, 840 KBLicence: CC BY

HOD1: Inferring relative treatment effects from combined randomised and observational data
Dias, S. D. D. S. (Principal investigator)
MEDICAL RESEARCH COUNCIL (MRC)
1/01/19 → 30/11/22
Project: Research project (funded) › Research

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Lees, J. S., Hanlon, P., Butterly, E., Wild, S. H., Mair, F. S., Taylor, R. S., Guthrie, B., Gillies, K., Dias, S., Welton, N. J., & McAllister, D. A. (2022). Effect of age, sex and morbidity count on trial attrition: meta-analysis of individual participant-level data from phase 3/4 industry-funded clinical trials. BMJ Medicine, 1, Article e000217. https://doi.org/10.1136/bmjmed-2022-000217

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AU - Lees, Jennifer S

AU - Hanlon, Peter

AU - Butterly, Elaine

AU - Wild, Sarah H.

AU - Mair, Frances S

AU - Taylor, Rod S

AU - Guthrie, Bruce

AU - Gillies, Katie

AU - Dias, Sofia

AU - Welton, Nicky J.

AU - McAllister, David A.

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M1 - e000217

ER -

Effect of age, sex and morbidity count on trial attrition: meta-analysis of individual participant-level data from phase 3/4 industry-funded clinical trials

Bibliographical note

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Projects

HOD1: Inferring relative treatment effects from combined randomised and observational data

Cite this