Effect of humidity on photoinduced radicals in human hair

Philip Groves; Jennifer M. Marsh; Yiping Sun; Tanuja Chaudhary; Victor Chechik

doi:10.1016/j.freeradbiomed.2018.04.548

Effect of humidity on photoinduced radicals in human hair

Philip Groves, Jennifer M. Marsh^*, Yiping Sun, Tanuja Chaudhary, Victor Chechik

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

EPR spectroscopy was used to monitor formation of free radicals in human hair upon UV irradiation. While the EPR spectra of brown hair were dominated by melanin signal, those of white hair were keratin-derived. The decay of UV induced keratin radicals was enhanced at increased ambient humidity. We argue that at higher humidity the swollen hair provides a more liquid-like environment, and higher molecular mobility in this environment leads to faster radical reactions. This interpretation is consistent with the increased UV-triggered protein damage in hair at high humidity as demonstrated by the protein loss, MALDI-TOF and FT-IR data.

Original language	English
Pages (from-to)	20-25
Number of pages	6
Journal	Free Radical Biology and Medicine
Volume	121
Early online date	13 Apr 2018
DOIs	https://doi.org/10.1016/j.freeradbiomed.2018.04.548
Publication status	Published - 1 Jun 2018

Bibliographical note

Keywords

Electron paramagnetic resonance
Free radicals
Hair
UV damage

Access to Document

10.1016/j.freeradbiomed.2018.04.548

UV Humidity Manuscript v3 - figures corrected
© 2018 Elsevier Inc. All rights reserved. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy.
Accepted author manuscript, 422 KBLicence: CC BY-NC-ND

Cite this

@article{d86e6a076b6140a293ded63928c7135c,

title = "Effect of humidity on photoinduced radicals in human hair",

abstract = "EPR spectroscopy was used to monitor formation of free radicals in human hair upon UV irradiation. While the EPR spectra of brown hair were dominated by melanin signal, those of white hair were keratin-derived. The decay of UV induced keratin radicals was enhanced at increased ambient humidity. We argue that at higher humidity the swollen hair provides a more liquid-like environment, and higher molecular mobility in this environment leads to faster radical reactions. This interpretation is consistent with the increased UV-triggered protein damage in hair at high humidity as demonstrated by the protein loss, MALDI-TOF and FT-IR data.",

keywords = "Electron paramagnetic resonance, Free radicals, Hair, UV damage",

author = "Philip Groves and Marsh, {Jennifer M.} and Yiping Sun and Tanuja Chaudhary and Victor Chechik",

note = "{\textcopyright} 2018 Elsevier Inc. All rights reserved. This is an author-produced version of the published paper. Uploaded in accordance with the publisher{\textquoteright}s self-archiving policy. ",

year = "2018",

month = jun,

day = "1",

doi = "10.1016/j.freeradbiomed.2018.04.548",

language = "English",

volume = "121",

pages = "20--25",

journal = "Free Radical Biology and Medicine",

issn = "0891-5849",

publisher = "Elsevier",

}

TY - JOUR

T1 - Effect of humidity on photoinduced radicals in human hair

AU - Groves, Philip

AU - Marsh, Jennifer M.

AU - Sun, Yiping

AU - Chaudhary, Tanuja

AU - Chechik, Victor

PY - 2018/6/1

Y1 - 2018/6/1

N2 - EPR spectroscopy was used to monitor formation of free radicals in human hair upon UV irradiation. While the EPR spectra of brown hair were dominated by melanin signal, those of white hair were keratin-derived. The decay of UV induced keratin radicals was enhanced at increased ambient humidity. We argue that at higher humidity the swollen hair provides a more liquid-like environment, and higher molecular mobility in this environment leads to faster radical reactions. This interpretation is consistent with the increased UV-triggered protein damage in hair at high humidity as demonstrated by the protein loss, MALDI-TOF and FT-IR data.

AB - EPR spectroscopy was used to monitor formation of free radicals in human hair upon UV irradiation. While the EPR spectra of brown hair were dominated by melanin signal, those of white hair were keratin-derived. The decay of UV induced keratin radicals was enhanced at increased ambient humidity. We argue that at higher humidity the swollen hair provides a more liquid-like environment, and higher molecular mobility in this environment leads to faster radical reactions. This interpretation is consistent with the increased UV-triggered protein damage in hair at high humidity as demonstrated by the protein loss, MALDI-TOF and FT-IR data.

KW - Electron paramagnetic resonance

KW - Free radicals

KW - Hair

KW - UV damage

UR - http://www.scopus.com/inward/record.url?scp=85046167597&partnerID=8YFLogxK

U2 - 10.1016/j.freeradbiomed.2018.04.548

DO - 10.1016/j.freeradbiomed.2018.04.548

M3 - Article

AN - SCOPUS:85046167597

SN - 0891-5849

VL - 121

SP - 20

EP - 25

JO - Free Radical Biology and Medicine

JF - Free Radical Biology and Medicine

ER -

Effect of humidity on photoinduced radicals in human hair

Abstract

Bibliographical note

Keywords

Access to Document

Other files and links

Cite this