Effects of PREPARE, a Multi-component, School-Based HIV and Intimate Partner Violence (IPV) Prevention Programme on Adolescent Sexual Risk Behaviour and IPV: Cluster Randomised Controlled Trial

Catherine Mathews, Sander M Eggers, Loraine Townsend, Leif E Aarø, Petrus J de Vries, Amanda J Mason-Jones, Petra De Koker, Tracy McClinton Appollis, Yolisa Mtshizana, Joy Koech, Annegreet Wubs, Hein De Vries

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Young South Africans, especially women, are at high risk of HIV. We evaluated the effects of PREPARE, a multi-component, school-based HIV prevention intervention to delay sexual debut, increase condom use and decrease intimate partner violence (IPV) among young adolescents. We conducted a cluster RCT among Grade eights in 42 high schools. The intervention comprised education sessions, a school health service and a school sexual violence prevention programme. Participants completed questionnaires at baseline, 6 and 12 months. Regression was undertaken to provide ORs or coefficients adjusted for clustering. Of 6244 sampled adolescents, 55.3 % participated. At 12 months there were no differences between intervention and control arms in sexual risk behaviours. Participants in the intervention arm were less likely to report IPV victimisation (35.1 vs. 40.9 %; OR 0.77, 95 % CI 0.61-0.99; t(40) = 2.14) suggesting the intervention shaped intimate partnerships into safer ones, potentially lowering the risk for HIV.

Original languageEnglish
Pages (from-to)1821-1840
Number of pages20
JournalAIDS and behavior
Issue number9
Early online date3 May 2016
Publication statusPublished - Sept 2016

Bibliographical note

© 2016, The authors.


  • Adolescents
  • HIV prevention
  • Intimate partner violence
  • Randomised controlled trial
  • Sexual risk behaviour
  • Humans
  • Sex Education/methods
  • Condoms/statistics & numerical data
  • Crime Victims
  • HIV Infections/prevention & control
  • Intimate Partner Violence/prevention & control
  • Sex Offenses
  • Risk-Taking
  • Adolescent
  • Safe Sex
  • Adult
  • Female
  • Surveys and Questionnaires
  • Adolescent Behavior
  • Sexual Behavior/psychology
  • Sexual Partners
  • School Health Services
  • Interpersonal Relations
  • Schools

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