ENANTIOSPECIFIC SYNTHESIS OF R-5,6-DIHYDROXY-2-(N,N-DI-NORMAL-PROPYLAMINO) AND S-5,6-DIHYDROXY-2-(N,N-DI-NORMAL-PROPYLAMINO)TETRALINS FROM SERINE

A D  BAXTER; P J  MURRAY; R J K  TAYLOR

ENANTIOSPECIFIC SYNTHESIS OF R-5,6-DIHYDROXY-2-(N,N-DI-NORMAL-PROPYLAMINO) AND S-5,6-DIHYDROXY-2-(N,N-DI-NORMAL-PROPYLAMINO)TETRALINS FROM SERINE

A D BAXTER, P J MURRAY, R J K TAYLOR

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

The first enantiospecific synthesis of 5,6-dihydroxy-2-(NN-di-n-propylamino)tetralin [5,6-(HO)2DPAT] is reported. Starting from D- or L-serine either enantiomer is readily available in high optical purity.

Original language	English
Pages (from-to)	2331-2334
Number of pages	4
Journal	Tetrahedron Letters
Volume	33
Issue number	17
Publication status	Published - 21 Apr 1992

Keywords

PENALDIC ACID EQUIVALENT
ALPHA-AMINO-ACIDS
AGONISTS

Cite this

@article{eed7a9c5988e4413ab75f5ff05a5a40f,

title = "ENANTIOSPECIFIC SYNTHESIS OF R-5,6-DIHYDROXY-2-(N,N-DI-NORMAL-PROPYLAMINO) AND S-5,6-DIHYDROXY-2-(N,N-DI-NORMAL-PROPYLAMINO)TETRALINS FROM SERINE",

abstract = "The first enantiospecific synthesis of 5,6-dihydroxy-2-(NN-di-n-propylamino)tetralin [5,6-(HO)2DPAT] is reported. Starting from D- or L-serine either enantiomer is readily available in high optical purity.",

keywords = "PENALDIC ACID EQUIVALENT, ALPHA-AMINO-ACIDS, AGONISTS",

author = "BAXTER, {A D} and MURRAY, {P J} and TAYLOR, {R J K}",

year = "1992",

month = apr,

day = "21",

language = "English",

volume = "33",

pages = "2331--2334",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier",

number = "17",

}

TY - JOUR

T1 - ENANTIOSPECIFIC SYNTHESIS OF R-5,6-DIHYDROXY-2-(N,N-DI-NORMAL-PROPYLAMINO) AND S-5,6-DIHYDROXY-2-(N,N-DI-NORMAL-PROPYLAMINO)TETRALINS FROM SERINE

AU - BAXTER, A D

AU - MURRAY, P J

AU - TAYLOR, R J K

PY - 1992/4/21

Y1 - 1992/4/21

N2 - The first enantiospecific synthesis of 5,6-dihydroxy-2-(NN-di-n-propylamino)tetralin [5,6-(HO)2DPAT] is reported. Starting from D- or L-serine either enantiomer is readily available in high optical purity.

AB - The first enantiospecific synthesis of 5,6-dihydroxy-2-(NN-di-n-propylamino)tetralin [5,6-(HO)2DPAT] is reported. Starting from D- or L-serine either enantiomer is readily available in high optical purity.

KW - PENALDIC ACID EQUIVALENT

KW - ALPHA-AMINO-ACIDS

KW - AGONISTS

M3 - Article

SN - 0040-4039

VL - 33

SP - 2331

EP - 2334

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 17

ER -