By the same authors

From the same journal

Endosomal trafficking of yeast membrane proteins

Research output: Contribution to journalArticle

Standard

Endosomal trafficking of yeast membrane proteins. / Laidlaw, Kamilla Margrethe Ebbesen; MacDonald, Chris.

In: Biochemical Society transactions, 31.10.2018.

Research output: Contribution to journalArticle

Harvard

Laidlaw, KME & MacDonald, C 2018, 'Endosomal trafficking of yeast membrane proteins', Biochemical Society transactions. https://doi.org/10.1042/BST20180258

APA

Laidlaw, K. M. E., & MacDonald, C. (2018). Endosomal trafficking of yeast membrane proteins. Biochemical Society transactions. https://doi.org/10.1042/BST20180258

Vancouver

Laidlaw KME, MacDonald C. Endosomal trafficking of yeast membrane proteins. Biochemical Society transactions. 2018 Oct 31. https://doi.org/10.1042/BST20180258

Author

Laidlaw, Kamilla Margrethe Ebbesen ; MacDonald, Chris. / Endosomal trafficking of yeast membrane proteins. In: Biochemical Society transactions. 2018.

Bibtex - Download

@article{22a72c517ce74d838c47fc435893459f,
title = "Endosomal trafficking of yeast membrane proteins",
abstract = "Various membrane trafficking pathways transport molecules through the endosomal system of eukaryotic cells, where trafficking decisions control the localisation and activity of a diverse repertoire of membrane protein cargoes. The budding yeast Saccharomyces cerevisiae has been used to discover and define many mechanisms that regulate conserved features of endosomal trafficking. Internalised surface membrane proteins first localise to endosomes before sorting to other compartments. Ubiquitination of endosomal membrane proteins is a signal for their degradation. Ubiquitinated cargoes are recognised by the endosomal sorting complex required for transport (ESCRT) apparatus, which mediate sorting through the multivesicular body pathway to the lysosome for degradation. Proteins that are not destined for degradation can be recycled to other intracellular compartments, such as the Golgi and the plasma membrane. In this review, we discuss recent developments elucidating the mechanisms that drive membrane protein degradation and recycling pathways in yeast.",
author = "Laidlaw, {Kamilla Margrethe Ebbesen} and Chris MacDonald",
note = "{\circledC} 2018 The Author(s). This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details.",
year = "2018",
month = "10",
day = "31",
doi = "10.1042/BST20180258",
language = "English",
journal = "Biochemical Society transactions",
issn = "0300-5127",
publisher = "Portland Press Ltd.",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Endosomal trafficking of yeast membrane proteins

AU - Laidlaw, Kamilla Margrethe Ebbesen

AU - MacDonald, Chris

N1 - © 2018 The Author(s). This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details.

PY - 2018/10/31

Y1 - 2018/10/31

N2 - Various membrane trafficking pathways transport molecules through the endosomal system of eukaryotic cells, where trafficking decisions control the localisation and activity of a diverse repertoire of membrane protein cargoes. The budding yeast Saccharomyces cerevisiae has been used to discover and define many mechanisms that regulate conserved features of endosomal trafficking. Internalised surface membrane proteins first localise to endosomes before sorting to other compartments. Ubiquitination of endosomal membrane proteins is a signal for their degradation. Ubiquitinated cargoes are recognised by the endosomal sorting complex required for transport (ESCRT) apparatus, which mediate sorting through the multivesicular body pathway to the lysosome for degradation. Proteins that are not destined for degradation can be recycled to other intracellular compartments, such as the Golgi and the plasma membrane. In this review, we discuss recent developments elucidating the mechanisms that drive membrane protein degradation and recycling pathways in yeast.

AB - Various membrane trafficking pathways transport molecules through the endosomal system of eukaryotic cells, where trafficking decisions control the localisation and activity of a diverse repertoire of membrane protein cargoes. The budding yeast Saccharomyces cerevisiae has been used to discover and define many mechanisms that regulate conserved features of endosomal trafficking. Internalised surface membrane proteins first localise to endosomes before sorting to other compartments. Ubiquitination of endosomal membrane proteins is a signal for their degradation. Ubiquitinated cargoes are recognised by the endosomal sorting complex required for transport (ESCRT) apparatus, which mediate sorting through the multivesicular body pathway to the lysosome for degradation. Proteins that are not destined for degradation can be recycled to other intracellular compartments, such as the Golgi and the plasma membrane. In this review, we discuss recent developments elucidating the mechanisms that drive membrane protein degradation and recycling pathways in yeast.

U2 - 10.1042/BST20180258

DO - 10.1042/BST20180258

M3 - Article

JO - Biochemical Society transactions

JF - Biochemical Society transactions

SN - 0300-5127

ER -