Epi-cyclophellitol cyclosulfate, a mechanism-based ER α-glucosidase II inhibitor, blocks replication of SARS-CoV-2 and other coronaviruses

Melissa Thaler, Tim P. Ofman, Ken Kok, Jurriaan J.A. Heming, Elisha Moran, Isabelle Pickles, Anouk A. Leijs, Adrianus M. C. H. van den Nieuwendijk, Richard J. B. H. N van den Berg, Gijs Ruijgrok, Zach Armstrong, Clarisse Salgado-Benvindo, Dennis K. Ninaber, Eric J. Snijder, Constant A. A. van Boeckel, Marta Artola, Gideon J. Davies, Herman S. Overkleeft, Martijn J. van Hemert

Chemistry

Research output: Contribution to journal › Article › peer-review

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CARBOCENTRE: Activity-Based Profiling of Glycoprocessing Enzymes for Human Health and a Sustainable Society
Davies, G. J. (Principal investigator)
EUROPEAN COMMISSION
1/06/21 → 31/05/27
Project: Research project (funded) › Research
RS Research Professorship
Davies, G. J. (Principal investigator)
THE ROYAL SOCIETY
1/01/17 → 31/12/26
Project: Research project (funded) › Research

Epi-cyclophellitol cyclosulfate, a mechanism-based ER α-glucosidase II inhibitor, blocks replication of SARS-CoV-2 and other coronaviruses

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CARBOCENTRE: Activity-Based Profiling of Glycoprocessing Enzymes for Human Health and a Sustainable Society

RS Research Professorship