Esters and amides from activated alcohols using manganese(IV) dioxide: Tandem oxidation processes

J S  Foot; H  Kanno; G M P  Giblin; R J K  Taylor

Esters and amides from activated alcohols using manganese(IV) dioxide: Tandem oxidation processes

J S Foot, H Kanno, G M P Giblin, R J K Taylor

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

Manganese(IV) dioxide can be used in conjunction with sodium cyanide in THF-methanol or in methanol alone for the direct conversion of activated alcohols into methyl esters. Ethyl and isopropyl esters can also be prepared. Similarly, use of manganese(IV) dioxide and sodium cyanide in THF containing ammonia or primary amines can be used to convert alcohols into the corresponding amides. Several activated alcohols and one non-activated alcohol example are reported.

Original language	English
Pages (from-to)	1055-1064
Number of pages	10
Journal	SYNTHESIS-STUTTGART
Issue number	7
Publication status	Published - May 2003

Keywords

alcohols
amides
esters
oxidations
tandem reactions
WITTIG REACTIONS
DIRECT CONVERSION
METHYL-ESTERS
SITU
ALDEHYDES
AMINES
REAGENTS
ROOTS

Cite this

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title = "Esters and amides from activated alcohols using manganese(IV) dioxide: Tandem oxidation processes",

abstract = "Manganese(IV) dioxide can be used in conjunction with sodium cyanide in THF-methanol or in methanol alone for the direct conversion of activated alcohols into methyl esters. Ethyl and isopropyl esters can also be prepared. Similarly, use of manganese(IV) dioxide and sodium cyanide in THF containing ammonia or primary amines can be used to convert alcohols into the corresponding amides. Several activated alcohols and one non-activated alcohol example are reported.",

keywords = "alcohols, amides, esters, oxidations, tandem reactions, WITTIG REACTIONS, DIRECT CONVERSION, METHYL-ESTERS, SITU, ALDEHYDES, AMINES, REAGENTS, ROOTS",

author = "Foot, {J S} and H Kanno and Giblin, {G M P} and Taylor, {R J K}",

year = "2003",

month = may,

language = "English",

pages = "1055--1064",

journal = "SYNTHESIS-STUTTGART",

issn = "0039-7881",

publisher = "Georg Thieme Verlag",

number = "7",

}

TY - JOUR

T1 - Esters and amides from activated alcohols using manganese(IV) dioxide: Tandem oxidation processes

AU - Foot, J S

AU - Kanno, H

AU - Giblin, G M P

AU - Taylor, R J K

PY - 2003/5

Y1 - 2003/5

N2 - Manganese(IV) dioxide can be used in conjunction with sodium cyanide in THF-methanol or in methanol alone for the direct conversion of activated alcohols into methyl esters. Ethyl and isopropyl esters can also be prepared. Similarly, use of manganese(IV) dioxide and sodium cyanide in THF containing ammonia or primary amines can be used to convert alcohols into the corresponding amides. Several activated alcohols and one non-activated alcohol example are reported.

AB - Manganese(IV) dioxide can be used in conjunction with sodium cyanide in THF-methanol or in methanol alone for the direct conversion of activated alcohols into methyl esters. Ethyl and isopropyl esters can also be prepared. Similarly, use of manganese(IV) dioxide and sodium cyanide in THF containing ammonia or primary amines can be used to convert alcohols into the corresponding amides. Several activated alcohols and one non-activated alcohol example are reported.

KW - alcohols

KW - amides

KW - esters

KW - oxidations

KW - tandem reactions

KW - WITTIG REACTIONS

KW - DIRECT CONVERSION

KW - METHYL-ESTERS

KW - SITU

KW - ALDEHYDES

KW - AMINES

KW - REAGENTS

KW - ROOTS

M3 - Article

SN - 0039-7881

SP - 1055

EP - 1064

JO - SYNTHESIS-STUTTGART

JF - SYNTHESIS-STUTTGART

IS - 7

ER -