By the same authors

From the same journal

eta(4)-Pyrone iron(0)carbonyl complexes as effective CO-releasing molecules (CO-RMs)

Research output: Contribution to journalArticlepeer-review

Standard

eta(4)-Pyrone iron(0)carbonyl complexes as effective CO-releasing molecules (CO-RMs). / Fairlamb, I J S ; Duhme-Klair, A K ; Lynam, J M ; Moulton, B E ; O'Brien, C T ; Sawle, P ; Hammad, J ; Motterlini, R .

In: Bioorganic & Medicinal Chemistry Letters, Vol. 16, No. 4, 15.02.2006, p. 995-998.

Research output: Contribution to journalArticlepeer-review

Harvard

Fairlamb, IJS, Duhme-Klair, AK, Lynam, JM, Moulton, BE, O'Brien, CT, Sawle, P, Hammad, J & Motterlini, R 2006, 'eta(4)-Pyrone iron(0)carbonyl complexes as effective CO-releasing molecules (CO-RMs)', Bioorganic & Medicinal Chemistry Letters, vol. 16, no. 4, pp. 995-998. https://doi.org/10.1016/j.bmcl.2005.10.085

APA

Fairlamb, I. J. S., Duhme-Klair, A. K., Lynam, J. M., Moulton, B. E., O'Brien, C. T., Sawle, P., Hammad, J., & Motterlini, R. (2006). eta(4)-Pyrone iron(0)carbonyl complexes as effective CO-releasing molecules (CO-RMs). Bioorganic & Medicinal Chemistry Letters, 16(4), 995-998. https://doi.org/10.1016/j.bmcl.2005.10.085

Vancouver

Fairlamb IJS, Duhme-Klair AK, Lynam JM, Moulton BE, O'Brien CT, Sawle P et al. eta(4)-Pyrone iron(0)carbonyl complexes as effective CO-releasing molecules (CO-RMs). Bioorganic & Medicinal Chemistry Letters. 2006 Feb 15;16(4):995-998. https://doi.org/10.1016/j.bmcl.2005.10.085

Author

Fairlamb, I J S ; Duhme-Klair, A K ; Lynam, J M ; Moulton, B E ; O'Brien, C T ; Sawle, P ; Hammad, J ; Motterlini, R . / eta(4)-Pyrone iron(0)carbonyl complexes as effective CO-releasing molecules (CO-RMs). In: Bioorganic & Medicinal Chemistry Letters. 2006 ; Vol. 16, No. 4. pp. 995-998.

Bibtex - Download

@article{e3136db65b0e40d482390501bd488910,
title = "eta(4)-Pyrone iron(0)carbonyl complexes as effective CO-releasing molecules (CO-RMs)",
abstract = "The CO-releasing properties of iron(0)tricarbonyl complexes bearing a 2-pyrone ligand have been evaluated. In this report, we demonstrate that the intrinsic stability of the (eta(4)-2-pyrone)Fe(CO)(3) Complex influences the extent and rate of CO release, which is affected by the presence of a halogen substituent on the 2-pyrone ring. The cell viability index has been highlighted for the active carbon monoxide-releasing molecules (CO-RMs), demonstrating that these complexes and related derivatives are a promising new class of compounds with potential therapeutic applications. (c) 2005 Elsevier Ltd. All rights reserved.",
keywords = "vasorelaxation, carbon monoxide, transiton metal carbonyl complexes, therapeutic agents, CARBON-MONOXIDE, HEME OXYGENASE-1, CHOLESTEROL ESTERASE, IN-VIVO, 2-PYRONES, PATHWAY",
author = "Fairlamb, {I J S} and Duhme-Klair, {A K} and Lynam, {J M} and Moulton, {B E} and O'Brien, {C T} and P Sawle and J Hammad and R Motterlini",
year = "2006",
month = feb,
day = "15",
doi = "10.1016/j.bmcl.2005.10.085",
language = "English",
volume = "16",
pages = "995--998",
journal = "Bioorganic & Medicinal Chemistry Letters",
issn = "0960-894X",
publisher = "Elsevier Limited",
number = "4",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - eta(4)-Pyrone iron(0)carbonyl complexes as effective CO-releasing molecules (CO-RMs)

AU - Fairlamb, I J S

AU - Duhme-Klair, A K

AU - Lynam, J M

AU - Moulton, B E

AU - O'Brien, C T

AU - Sawle, P

AU - Hammad, J

AU - Motterlini, R

PY - 2006/2/15

Y1 - 2006/2/15

N2 - The CO-releasing properties of iron(0)tricarbonyl complexes bearing a 2-pyrone ligand have been evaluated. In this report, we demonstrate that the intrinsic stability of the (eta(4)-2-pyrone)Fe(CO)(3) Complex influences the extent and rate of CO release, which is affected by the presence of a halogen substituent on the 2-pyrone ring. The cell viability index has been highlighted for the active carbon monoxide-releasing molecules (CO-RMs), demonstrating that these complexes and related derivatives are a promising new class of compounds with potential therapeutic applications. (c) 2005 Elsevier Ltd. All rights reserved.

AB - The CO-releasing properties of iron(0)tricarbonyl complexes bearing a 2-pyrone ligand have been evaluated. In this report, we demonstrate that the intrinsic stability of the (eta(4)-2-pyrone)Fe(CO)(3) Complex influences the extent and rate of CO release, which is affected by the presence of a halogen substituent on the 2-pyrone ring. The cell viability index has been highlighted for the active carbon monoxide-releasing molecules (CO-RMs), demonstrating that these complexes and related derivatives are a promising new class of compounds with potential therapeutic applications. (c) 2005 Elsevier Ltd. All rights reserved.

KW - vasorelaxation

KW - carbon monoxide

KW - transiton metal carbonyl complexes

KW - therapeutic agents

KW - CARBON-MONOXIDE

KW - HEME OXYGENASE-1

KW - CHOLESTEROL ESTERASE

KW - IN-VIVO

KW - 2-PYRONES

KW - PATHWAY

U2 - 10.1016/j.bmcl.2005.10.085

DO - 10.1016/j.bmcl.2005.10.085

M3 - Article

VL - 16

SP - 995

EP - 998

JO - Bioorganic & Medicinal Chemistry Letters

JF - Bioorganic & Medicinal Chemistry Letters

SN - 0960-894X

IS - 4

ER -