Expression and localisation of aquaporin water channels in human urothelium in situ and in vitro

Peter C Rubenwolf, Nikolaos T Georgopoulos, Lisa A Clements, Sally Feather, Philip Holland, David F M Thomas, Jennifer Southgate

Research output: Contribution to journalArticlepeer-review


Urothelium is generally considered to be impermeable to water and constituents of urine. The possibility that human urothelium expresses aquaporin (AQP) water channels as the basis for water and solute transport has not previously been investigated.
Original languageEnglish
Pages (from-to)1013-23
Number of pages11
JournalEuropean Urology Supplements
Issue number6
Publication statusPublished - Dec 2009


  • Aquaporins
  • Cell Differentiation
  • Cell Division
  • Cell Line
  • Epithelial Cells
  • Gene Expression
  • Humans
  • Immunohistochemistry
  • Reverse Transcriptase Polymerase Chain Reaction
  • Urinary Bladder
  • Urothelium
  • Water

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