Research output: Contribution to journal › Article › peer-review
Journal | Tetrahedron |
---|---|
Date | Published - 6 Feb 2010 |
Issue number | 6 |
Volume | 66 |
Number of pages | 8 |
Pages (from-to) | 1357-1364 |
Original language | English |
The study of the reaction with MeONa/MeOH of chlorinated gamma-lactams. prepared from the atom transfer radical cyclization of N-allyl-alpha-perchloroamides, has been extended to the case of substiates carrying an exo halogen atom on a branched carbon Only with secondary exo C-Cl groups, that are not located on a fused ring, does the functional rearrangement follow the typical transformation route, Which With trichloro-lactams can proceed further to give 4-alkylidene derivatives From a practical point of view, the outcome of the reaction with di- or trichloio N-cinnamylamides is synthetically valuable, affording the 5-methoxy-IH-pyrrol-2(5H)-one or 3-benzylidenepyrrlidine-2.5-dione. respectively. in good to excellent yield (C) 2009 Elsevier Ltd All rights reserved
Find related publications, people, projects, datasets and more using interactive charts.