Gd-functionalised Au nanoparticles as targeted contrast agents in MRI: relaxivity enhancement by polyelectrolyte coating

Muhammad Farooq Warsi, Ralph W. Adams, Simon B. Duckett, Victor Chechik

Research output: Contribution to journalArticlepeer-review

Abstract

Monolayer-protected, Gd3+-functionalised gold nanoparticles with enhanced spin-lattice relaxivity (r(1)) were prepared; adsorption of polyelectrolytes on these materials further increased r(1) and ligand exchange with a biotin-derivatised disulfide led to a prototype avidin-targeted contrast agent.

Original languageEnglish
Pages (from-to)451-453
Number of pages3
JournalChemical Communications
Volume46
Issue number3
DOIs
Publication statusPublished - 2010

Keywords

  • GOLD NANOPARTICLES
  • MICROCAPSULES
  • DYNAMICS
  • DESIGN
  • LIGAND

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