Gene discovery and virus induced gene silencing reveal branched pathways to major classes of bioactive diterpenoids in Euphorbia peplus

Tomasz Czechowski; Edith Catherine Felicie Forestier; Sandesh Swamidatta; A.D. Gilday; Amy Cording; Tony Larson; D. Harvey; Yi Li; Zhesi He; Andrew J King; Geoffrey D. Brown; Ian Alexander Graham

doi:10.1073/pnas.2203890119

Gene discovery and virus induced gene silencing reveal branched pathways to major classes of bioactive diterpenoids in Euphorbia peplus

Tomasz Czechowski, Edith Catherine Felicie Forestier, Sandesh Swamidatta, A.D. Gilday, Amy Cording, Tony Larson, D. Harvey, Yi Li, Zhesi He, Andrew J King, Geoffrey D. Brown, Ian Alexander Graham

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	e2203890119
Number of pages	7
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	119
Issue number	21
DOIs	https://doi.org/10.1073/pnas.2203890119
Publication status	Published - 18 May 2022

Bibliographical note

Keywords

terpenoids
short-chain dehydrogenases/reductases
cytochrome P450 oxidase
gene clusters
virus induced gene silencing

Access to Document

10.1073/pnas.2203890119Licence: CC BY

pnas.2203890119
© 2022 the Author(s). Published by PNAS.
Final published version, 1.35 MBLicence: CC BY

Developing platforms for the production of diterpenoids
Graham, I. A. & Smith, M.
BBSRC (BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL)
1/04/15 → 30/09/21
Project: Research project (funded) › Research

Data underpinning 'Gene discovery and virus-induced gene silencing reveal branched pathways to major classes of bioactive diterpenoids in Euphorbia peplus
Graham, I. A. (Supervisor), Czechowski, T. (Contributor) & Li, Y. (Contributor), National Library of Medicine, 25 Mar 2022
https://www.ncbi.nlm.nih.gov/bioproject/?term=PRJNA819961
Dataset

Cite this

Czechowski, T., Forestier, E. C. F., Swamidatta, S., Gilday, A. D., Cording, A., Larson, T., Harvey, D., Li, Y., He, Z., King, A. J., Brown, G. D., & Graham, I. A. (2022). Gene discovery and virus induced gene silencing reveal branched pathways to major classes of bioactive diterpenoids in Euphorbia peplus. Proceedings of the National Academy of Sciences of the United States of America, 119(21), Article e2203890119. https://doi.org/10.1073/pnas.2203890119

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title = "Gene discovery and virus induced gene silencing reveal branched pathways to major classes of bioactive diterpenoids in Euphorbia peplus",

keywords = "terpenoids, short-chain dehydrogenases/reductases, cytochrome P450 oxidase, gene clusters, virus induced gene silencing",

author = "Tomasz Czechowski and Forestier, {Edith Catherine Felicie} and Sandesh Swamidatta and A.D. Gilday and Amy Cording and Tony Larson and D. Harvey and Yi Li and Zhesi He and King, {Andrew J} and Brown, {Geoffrey D.} and Graham, {Ian Alexander}",

note = "{\textcopyright} 2022 the Author(s). Published by PNAS. ",

year = "2022",

month = may,

day = "18",

doi = "10.1073/pnas.2203890119",

language = "English",

volume = "119",

journal = "Proceedings of the National Academy of Sciences of the United States of America",

issn = "0027-8424",

publisher = "National Academy of Sciences",

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Czechowski, T , Forestier, ECF , Swamidatta, S, Gilday, AD, Cording, A, Larson, T, Harvey, D, Li, Y , He, Z , King, AJ, Brown, GD & Graham, IA 2022, 'Gene discovery and virus induced gene silencing reveal branched pathways to major classes of bioactive diterpenoids in Euphorbia peplus', Proceedings of the National Academy of Sciences of the United States of America, vol. 119, no. 21, e2203890119. https://doi.org/10.1073/pnas.2203890119

Gene discovery and virus induced gene silencing reveal branched pathways to major classes of bioactive diterpenoids in Euphorbia peplus. / Czechowski, Tomasz ; Forestier, Edith Catherine Felicie ; Swamidatta, Sandesh et al.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 21, e2203890119, 18.05.2022.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Gene discovery and virus induced gene silencing reveal branched pathways to major classes of bioactive diterpenoids in Euphorbia peplus

AU - Czechowski, Tomasz

AU - Forestier, Edith Catherine Felicie

AU - Swamidatta, Sandesh

AU - Gilday, A.D.

AU - Cording, Amy

AU - Larson, Tony

AU - Harvey, D.

AU - Li, Yi

AU - He, Zhesi

AU - King, Andrew J

AU - Brown, Geoffrey D.

AU - Graham, Ian Alexander

PY - 2022/5/18

Y1 - 2022/5/18

KW - terpenoids

KW - short-chain dehydrogenases/reductases

KW - cytochrome P450 oxidase

KW - gene clusters

KW - virus induced gene silencing

U2 - 10.1073/pnas.2203890119

DO - 10.1073/pnas.2203890119

M3 - Article

SN - 0027-8424

VL - 119

JO - Proceedings of the National Academy of Sciences of the United States of America

JF - Proceedings of the National Academy of Sciences of the United States of America

IS - 21

M1 - e2203890119

ER -

Gene discovery and virus induced gene silencing reveal branched pathways to major classes of bioactive diterpenoids in Euphorbia peplus

Bibliographical note

Keywords

Access to Document

Projects

Developing platforms for the production of diterpenoids

Datasets

Data underpinning 'Gene discovery and virus-induced gene silencing reveal branched pathways to major classes of bioactive diterpenoids in Euphorbia peplus

Cite this