General anaesthesia versus local anaesthesia for carotid surgery (GALA): a multicentre, randomised controlled trial

S C Lewis, C P Warlow, A R Bodenham, B Colam, P M Rothwell, D Torgerson, D Dellagrammaticas, M Horrocks, C Liapis, A P Banning, M Gough, M J Gough, GALA Trial Collaborative Group

Research output: Contribution to journalArticlepeer-review


The effect of carotid endarterectomy in lowering the risk of stroke ipsilateral to severe atherosclerotic carotid-artery stenosis is offset by complications during or soon after surgery. We compared surgery under general anaesthesia with that under local anaesthesia because prediction and avoidance of perioperative strokes might be easier under local anaesthesia than under general anaesthesia.
Original languageEnglish
Pages (from-to)2132-2142
Number of pages11
Issue number9656
Publication statusPublished - 20 Dec 2008


  • Aged
  • Anesthesia, General
  • Anesthesia, Local
  • Carotid Stenosis
  • Endarterectomy, Carotid
  • Female
  • Humans
  • Male
  • Postoperative Complications
  • Stroke

Cite this