Genital human papillomavirus genotypes in northwestern Tanzania

Philippe Mayaud; Helen A Weiss; Charles J N Lacey; Dilbinder K Gill; David C W Mabey

Genital human papillomavirus genotypes in northwestern Tanzania

Philippe Mayaud, Helen A Weiss, Charles J N Lacey, Dilbinder K Gill, David C W Mabey

The Hull York Medical School

Research output: Contribution to journal › Article › peer-review

Abstract

Using MY09-MY11 PCR and human papillomavirus (HPV) typing by reverse blot hybridization, we found a 34% cervical HPV prevalence among 561 pregnant women in Tanzania. One hundred three of 123 women (84%) with typeable samples harbored high-risk oncogenic strains. HPV type 16 (HPV-16) was the most prevalent subtype (18%) among HPV-infected women and among women with cervical neoplasia (3 of 19). A multivalent vaccine for HPV-16, -18, -31, -33, and -35 would be necessary to prevent 50% of the neoplasia in this population.

Original language	English
Pages (from-to)	4451-3
Number of pages	3
Journal	Journal of clinical microbiology
Volume	41
Issue number	9
Publication status	Published - 2003

Keywords

Adolescent
Adult
Female
Genotype
Humans
Papillomaviridae
Papillomavirus Infections
Polymerase Chain Reaction
Uterine Cervical Neoplasms
Vagina

Cite this

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title = "Genital human papillomavirus genotypes in northwestern Tanzania",

abstract = "Using MY09-MY11 PCR and human papillomavirus (HPV) typing by reverse blot hybridization, we found a 34% cervical HPV prevalence among 561 pregnant women in Tanzania. One hundred three of 123 women (84%) with typeable samples harbored high-risk oncogenic strains. HPV type 16 (HPV-16) was the most prevalent subtype (18%) among HPV-infected women and among women with cervical neoplasia (3 of 19). A multivalent vaccine for HPV-16, -18, -31, -33, and -35 would be necessary to prevent 50% of the neoplasia in this population.",

keywords = "Adolescent, Adult, Female, Genotype, Humans, Papillomaviridae, Papillomavirus Infections, Polymerase Chain Reaction, Uterine Cervical Neoplasms, Vagina",

author = "Philippe Mayaud and Weiss, {Helen A} and Lacey, {Charles J N} and Gill, {Dilbinder K} and Mabey, {David C W}",

year = "2003",

language = "English",

volume = "41",

pages = "4451--3",

journal = "Journal of clinical microbiology",

issn = "0095-1137",

publisher = "American Society for Microbiology",

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TY - JOUR

T1 - Genital human papillomavirus genotypes in northwestern Tanzania

AU - Mayaud, Philippe

AU - Weiss, Helen A

AU - Lacey, Charles J N

AU - Gill, Dilbinder K

AU - Mabey, David C W

PY - 2003

Y1 - 2003

N2 - Using MY09-MY11 PCR and human papillomavirus (HPV) typing by reverse blot hybridization, we found a 34% cervical HPV prevalence among 561 pregnant women in Tanzania. One hundred three of 123 women (84%) with typeable samples harbored high-risk oncogenic strains. HPV type 16 (HPV-16) was the most prevalent subtype (18%) among HPV-infected women and among women with cervical neoplasia (3 of 19). A multivalent vaccine for HPV-16, -18, -31, -33, and -35 would be necessary to prevent 50% of the neoplasia in this population.

AB - Using MY09-MY11 PCR and human papillomavirus (HPV) typing by reverse blot hybridization, we found a 34% cervical HPV prevalence among 561 pregnant women in Tanzania. One hundred three of 123 women (84%) with typeable samples harbored high-risk oncogenic strains. HPV type 16 (HPV-16) was the most prevalent subtype (18%) among HPV-infected women and among women with cervical neoplasia (3 of 19). A multivalent vaccine for HPV-16, -18, -31, -33, and -35 would be necessary to prevent 50% of the neoplasia in this population.

KW - Adolescent

KW - Adult

KW - Female

KW - Genotype

KW - Humans

KW - Papillomaviridae

KW - Papillomavirus Infections

KW - Polymerase Chain Reaction

KW - Uterine Cervical Neoplasms

KW - Vagina

M3 - Article

C2 - 12958291

SN - 0095-1137

VL - 41

SP - 4451

EP - 4453

JO - Journal of clinical microbiology

JF - Journal of clinical microbiology

IS - 9

ER -