By the same authors

From the same journal

Genome analyses highlight the different biological roles of cellulases

Research output: Contribution to journalLiterature review

Published copy (DOI)

Author(s)

Department/unit(s)

Publication details

JournalNature reviews. Microbiology
DatePublished - Mar 2012
Issue number3
Volume10
Number of pages8
Pages (from-to)227-U
Original languageEnglish

Abstract

Cellulolytic enzymes have been the subject of renewed interest owing to their potential role in the conversion of plant lignocellulose to sustainable biofuels. An analysis of similar to 1,500 complete bacterial genomes, presented here, reveals that similar to 40% of the genomes of sequenced bacteria encode at least one cellulase gene. Most of the bacteria that encode cellulases are soil and marine saprophytes, many of which encode a range of enzymes for cellulose hydrolysis and also for the breakdown of the other constituents of plant cell walls (hemicelluloses and pectins). Intriguingly, cellulases are present in organisms that are usually considered as non-saprophytic, such as Mycobacterium tuberculosis, Legionella pneumophila, Yersinia pestis and even Escherichia coli. We also discuss newly emerging roles of cellulases in such non-saprophytic organisms.

    Research areas

  • CELLULOSE SYNTHASE, SYNCHROTRON X-RAY, ACETOBACTER-XYLINUM, NEUTRON FIBER DIFFRACTION, MYCOBACTERIUM-TUBERCULOSIS, HYDROGEN-BONDING SYSTEM, CLASSIFICATION, ENDO-1,4-BETA-D-GLUCANASE, CRYSTAL-STRUCTURE, PLANT-CELL WALLS

Projects

Discover related content

Find related publications, people, projects, datasets and more using interactive charts.

View graph of relations