Genomic architecture and introgression shape a butterfly radiation

Nathaniel Edelman; Paul Frandsen; Michael Miyagi; Bernardo Clavijo; John William Davey; Rebecca Dikow; Gonzalo García-Accinelli; Steven M. Van Bellegham; Nick Patterson; Daniel E. Neafsey; Richard John Challis; Sujai Kumar; Gilson R.P. Moreira; Camilo Salazar; Mathieu Chouteau; Brian A. Counterman; Riccardo Papa; Mark Blaxter; Robert D. Reed; Kanchon Kumar Dasmahapatra; Marcus R. Kronforst; Mathieu Joron; Chris D. Jiggins; W. Owen McMillan; Federica Di Palma; Andrew J. Blumberg; John Wakeley; David Jaffe; James Mallet

doi:10.1126/science.aaw2090

Genomic architecture and introgression shape a butterfly radiation

Nathaniel Edelman, Paul Frandsen, Michael Miyagi, Bernardo Clavijo, John William Davey, Rebecca Dikow, Gonzalo García-Accinelli, Steven M. Van Bellegham, Nick Patterson, Daniel E. Neafsey, Richard John Challis, Sujai Kumar, Gilson R.P. Moreira, Camilo Salazar, Mathieu Chouteau, Brian A. Counterman, Riccardo Papa, Mark Blaxter, Robert D. Reed, Kanchon Kumar DasmahapatraMarcus R. Kronforst, Mathieu Joron, Chris D. Jiggins, W. Owen McMillan, Federica Di Palma, Andrew J. Blumberg, John Wakeley, David Jaffe, James Mallet

Biology

Research output: Contribution to journal › Article › peer-review

Abstract

We use twenty de novo genome assemblies to probe the speciation history and architecture of gene flow in rapidly radiating Heliconius butterflies. Our tests to distinguish incomplete lineage sorting from introgression indicate that gene flow has obscured several ancient phylogenetic relationships in this group over large swathes of the genome. Introgressed loci are underrepresented in low recombination and gene-rich regions, consistent with the purging of
foreign alleles more tightly linked to incompatibility loci. We identify a hitherto unknown inversion that traps a color pattern switch locus. We infer that this inversion was transferred between lineages via introgression and is convergent with a similar rearrangement in another part of the genus. These multiple de novo genome sequences enable improved understanding of the
importance of introgression and selective processes in adaptive radiation.

Original language	English
Pages (from-to)	594-599
Journal	Science
Volume	366
Issue number	6465
DOIs	https://doi.org/10.1126/science.aaw2090
Publication status	Published - 1 Nov 2019

Bibliographical note

© 2019 The Authors. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details.

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10.1126/science.aaw2090

Dasmahapatra - edelman et al_science_revision_full_20190903
© 2019 The Authors. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details.
Accepted author manuscript, 10.8 MB

Data from: Recombination rate variation shapes barriers to introgression across butterfly genomes
Martin, S. H. (Creator), Davey, J. W. (Creator), Salazar, C. (Creator) & Jiggins, C. D. (Creator), Dryad, 29 Jul 2020
DOI: 10.5061/dryad.sk2pd88
Dataset

Cite this

Edelman, N., Frandsen, P., Miyagi, M., Clavijo, B., Davey, J. W., Dikow, R., García-Accinelli, G., Van Bellegham, S. M., Patterson, N., Neafsey, D. E., Challis, R. J., Kumar, S., Moreira, G. R. P., Salazar, C., Chouteau, M., Counterman, B. A., Papa, R., Blaxter, M., Reed, R. D., ... Mallet, J. (2019). Genomic architecture and introgression shape a butterfly radiation. Science, 366(6465), 594-599. https://doi.org/10.1126/science.aaw2090

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title = "Genomic architecture and introgression shape a butterfly radiation",

abstract = "We use twenty de novo genome assemblies to probe the speciation history and architecture of gene flow in rapidly radiating Heliconius butterflies. Our tests to distinguish incomplete lineage sorting from introgression indicate that gene flow has obscured several ancient phylogenetic relationships in this group over large swathes of the genome. Introgressed loci are underrepresented in low recombination and gene-rich regions, consistent with the purging offoreign alleles more tightly linked to incompatibility loci. We identify a hitherto unknown inversion that traps a color pattern switch locus. We infer that this inversion was transferred between lineages via introgression and is convergent with a similar rearrangement in another part of the genus. These multiple de novo genome sequences enable improved understanding of theimportance of introgression and selective processes in adaptive radiation.",

author = "Nathaniel Edelman and Paul Frandsen and Michael Miyagi and Bernardo Clavijo and Davey, {John William} and Rebecca Dikow and Gonzalo Garc{\'i}a-Accinelli and {Van Bellegham}, {Steven M.} and Nick Patterson and Neafsey, {Daniel E.} and Challis, {Richard John} and Sujai Kumar and Moreira, {Gilson R.P.} and Camilo Salazar and Mathieu Chouteau and Counterman, {Brian A.} and Riccardo Papa and Mark Blaxter and Reed, {Robert D.} and Dasmahapatra, {Kanchon Kumar} and Kronforst, {Marcus R.} and Mathieu Joron and Jiggins, {Chris D.} and McMillan, {W. Owen} and {Di Palma}, Federica and Blumberg, {Andrew J.} and John Wakeley and David Jaffe and James Mallet",

note = "{\textcopyright} 2019 The Authors. This is an author-produced version of the published paper. Uploaded in accordance with the publisher{\textquoteright}s self-archiving policy. Further copying may not be permitted; contact the publisher for details. ",

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doi = "10.1126/science.aaw2090",

language = "English",

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Edelman, N, Frandsen, P, Miyagi, M, Clavijo, B, Davey, JW, Dikow, R, García-Accinelli, G, Van Bellegham, SM, Patterson, N, Neafsey, DE, Challis, RJ, Kumar, S, Moreira, GRP, Salazar, C, Chouteau, M, Counterman, BA, Papa, R, Blaxter, M, Reed, RD, Dasmahapatra, KK, Kronforst, MR, Joron, M, Jiggins, CD, McMillan, WO, Di Palma, F, Blumberg, AJ, Wakeley, J, Jaffe, D & Mallet, J 2019, 'Genomic architecture and introgression shape a butterfly radiation', Science, vol. 366, no. 6465, pp. 594-599. https://doi.org/10.1126/science.aaw2090

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T1 - Genomic architecture and introgression shape a butterfly radiation

AU - Edelman, Nathaniel

AU - Frandsen, Paul

AU - Miyagi, Michael

AU - Clavijo, Bernardo

AU - Davey, John William

AU - Dikow, Rebecca

AU - García-Accinelli, Gonzalo

AU - Van Bellegham, Steven M.

AU - Patterson, Nick

AU - Neafsey, Daniel E.

AU - Challis, Richard John

AU - Kumar, Sujai

AU - Moreira, Gilson R.P.

AU - Salazar, Camilo

AU - Chouteau, Mathieu

AU - Counterman, Brian A.

AU - Papa, Riccardo

AU - Blaxter, Mark

AU - Reed, Robert D.

AU - Dasmahapatra, Kanchon Kumar

AU - Kronforst, Marcus R.

AU - Joron, Mathieu

AU - Jiggins, Chris D.

AU - McMillan, W. Owen

AU - Di Palma, Federica

AU - Blumberg, Andrew J.

AU - Wakeley, John

AU - Jaffe, David

AU - Mallet, James

N1 - © 2019 The Authors. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details.

PY - 2019/11/1

Y1 - 2019/11/1

N2 - We use twenty de novo genome assemblies to probe the speciation history and architecture of gene flow in rapidly radiating Heliconius butterflies. Our tests to distinguish incomplete lineage sorting from introgression indicate that gene flow has obscured several ancient phylogenetic relationships in this group over large swathes of the genome. Introgressed loci are underrepresented in low recombination and gene-rich regions, consistent with the purging offoreign alleles more tightly linked to incompatibility loci. We identify a hitherto unknown inversion that traps a color pattern switch locus. We infer that this inversion was transferred between lineages via introgression and is convergent with a similar rearrangement in another part of the genus. These multiple de novo genome sequences enable improved understanding of theimportance of introgression and selective processes in adaptive radiation.

AB - We use twenty de novo genome assemblies to probe the speciation history and architecture of gene flow in rapidly radiating Heliconius butterflies. Our tests to distinguish incomplete lineage sorting from introgression indicate that gene flow has obscured several ancient phylogenetic relationships in this group over large swathes of the genome. Introgressed loci are underrepresented in low recombination and gene-rich regions, consistent with the purging offoreign alleles more tightly linked to incompatibility loci. We identify a hitherto unknown inversion that traps a color pattern switch locus. We infer that this inversion was transferred between lineages via introgression and is convergent with a similar rearrangement in another part of the genus. These multiple de novo genome sequences enable improved understanding of theimportance of introgression and selective processes in adaptive radiation.

U2 - 10.1126/science.aaw2090

DO - 10.1126/science.aaw2090

M3 - Article

SN - 0036-8075

VL - 366

SP - 594

EP - 599

JO - Science

JF - Science

IS - 6465

ER -

Genomic architecture and introgression shape a butterfly radiation

Abstract

Bibliographical note

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Datasets

Data from: Recombination rate variation shapes barriers to introgression across butterfly genomes

Cite this