Geste antagoniste effects on motor performance in dystonia—a kinematic study

Rachel Newby; Siti Anizah Muhamed; Jane Elizabeth Alty; Jeremy Cosgrove; Stephen Leslie Smith; Peter Kempster

doi:10.1002/mdc3.13505

Geste antagoniste effects on motor performance in dystonia—a kinematic study

Rachel Newby, Siti Anizah Muhamed, Jane Elizabeth Alty, Jeremy Cosgrove, Stephen Leslie Smith, Peter Kempster

Electronic Engineering

Research output: Contribution to journal › Article › peer-review

Abstract

Background: The kinematic effects of gestes antagonistes in dystonia have not
previously been studied.
Objective: A kinematic investigation of the influence of the geste in patients with
organic and functional dystonia.
Methods: Twenty-six patients with dystonia (23 organic, 3 functional) associated with a geste were studied. Twenty-nine healthy controls also participated. Fifteen seconds of finger tapping was recorded by electromagnetic sensors, and the task was repeated with geste. Separable motor components (amplitude x frequency, coefficient of variation for amplitude and velocity, halts, and hesitations) were extracted using a customwritten MATLAB script. Performance with and without geste was compared using Wilcoxon signed ranks testing.
Results: When patients with organic dystonia executed their geste, speed of movement (amplitude x frequency) increased (p<0.0001), and halts decreased (p = 0.008). A similar trend was observed in the functional group.
Conclusions: Finger tapping is swifter and less halting with activation of a geste.

Original language	English
Pages (from-to)	759-764
Number of pages	6
Journal	Movement Disorders Clinical Practice
Early online date	10 Jun 2022
DOIs	https://doi.org/10.1002/mdc3.13505
Publication status	Published - 3 Aug 2022

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Movement Disord Clin Pract - 2022 - Newby - Geste Antagoniste Effects on Motor Performance in Dystonia A Kinematic Study
© 2022 The Authors.
Final published version, 297 KBLicence: CC BY

Cite this

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title = "Geste antagoniste effects on motor performance in dystonia—a kinematic study",

abstract = "Background: The kinematic effects of gestes antagonistes in dystonia have notpreviously been studied.Objective: A kinematic investigation of the influence of the geste in patients withorganic and functional dystonia.Methods: Twenty-six patients with dystonia (23 organic, 3 functional) associated with a geste were studied. Twenty-nine healthy controls also participated. Fifteen seconds of finger tapping was recorded by electromagnetic sensors, and the task was repeated with geste. Separable motor components (amplitude x frequency, coefficient of variation for amplitude and velocity, halts, and hesitations) were extracted using a customwritten MATLAB script. Performance with and without geste was compared using Wilcoxon signed ranks testing.Results: When patients with organic dystonia executed their geste, speed of movement (amplitude x frequency) increased (p<0.0001), and halts decreased (p = 0.008). A similar trend was observed in the functional group.Conclusions: Finger tapping is swifter and less halting with activation of a geste.",

author = "Rachel Newby and Muhamed, {Siti Anizah} and Alty, {Jane Elizabeth} and Jeremy Cosgrove and Smith, {Stephen Leslie} and Peter Kempster",

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doi = "10.1002/mdc3.13505",

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T1 - Geste antagoniste effects on motor performance in dystonia—a kinematic study

AU - Newby, Rachel

AU - Muhamed, Siti Anizah

AU - Alty, Jane Elizabeth

AU - Cosgrove, Jeremy

AU - Smith, Stephen Leslie

AU - Kempster, Peter

PY - 2022/8/3

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N2 - Background: The kinematic effects of gestes antagonistes in dystonia have notpreviously been studied.Objective: A kinematic investigation of the influence of the geste in patients withorganic and functional dystonia.Methods: Twenty-six patients with dystonia (23 organic, 3 functional) associated with a geste were studied. Twenty-nine healthy controls also participated. Fifteen seconds of finger tapping was recorded by electromagnetic sensors, and the task was repeated with geste. Separable motor components (amplitude x frequency, coefficient of variation for amplitude and velocity, halts, and hesitations) were extracted using a customwritten MATLAB script. Performance with and without geste was compared using Wilcoxon signed ranks testing.Results: When patients with organic dystonia executed their geste, speed of movement (amplitude x frequency) increased (p<0.0001), and halts decreased (p = 0.008). A similar trend was observed in the functional group.Conclusions: Finger tapping is swifter and less halting with activation of a geste.

AB - Background: The kinematic effects of gestes antagonistes in dystonia have notpreviously been studied.Objective: A kinematic investigation of the influence of the geste in patients withorganic and functional dystonia.Methods: Twenty-six patients with dystonia (23 organic, 3 functional) associated with a geste were studied. Twenty-nine healthy controls also participated. Fifteen seconds of finger tapping was recorded by electromagnetic sensors, and the task was repeated with geste. Separable motor components (amplitude x frequency, coefficient of variation for amplitude and velocity, halts, and hesitations) were extracted using a customwritten MATLAB script. Performance with and without geste was compared using Wilcoxon signed ranks testing.Results: When patients with organic dystonia executed their geste, speed of movement (amplitude x frequency) increased (p<0.0001), and halts decreased (p = 0.008). A similar trend was observed in the functional group.Conclusions: Finger tapping is swifter and less halting with activation of a geste.

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