Geste antagoniste effects on motor performance in dystonia—a kinematic study

Rachel Newby, Siti Anizah Muhamed, Jane Elizabeth Alty, Jeremy Cosgrove, Stephen Leslie Smith, Peter Kempster

Research output: Contribution to journalArticlepeer-review


Background: The kinematic effects of gestes antagonistes in dystonia have not
previously been studied.
Objective: A kinematic investigation of the influence of the geste in patients with
organic and functional dystonia.
Methods: Twenty-six patients with dystonia (23 organic, 3 functional) associated with a geste were studied. Twenty-nine healthy controls also participated. Fifteen seconds of finger tapping was recorded by electromagnetic sensors, and the task was repeated with geste. Separable motor components (amplitude x frequency, coefficient of variation for amplitude and velocity, halts, and hesitations) were extracted using a customwritten MATLAB script. Performance with and without geste was compared using Wilcoxon signed ranks testing.
Results: When patients with organic dystonia executed their geste, speed of movement (amplitude x frequency) increased (p<0.0001), and halts decreased (p = 0.008). A similar trend was observed in the functional group.
Conclusions: Finger tapping is swifter and less halting with activation of a geste.
Original languageEnglish
Pages (from-to)759-764
Number of pages6
JournalMovement Disorders Clinical Practice
Early online date10 Jun 2022
Publication statusPublished - 3 Aug 2022

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