Glycosyltransferases: managers of small molecules

D Bowles; J Isayenkova; E K Lim; B Poppenberger

doi:10.1016/j.pbi.2005.03.007

Glycosyltransferases: managers of small molecules

D Bowles, J Isayenkova, E K Lim, B Poppenberger

CNAP

Research output: Contribution to journal › Literature review › peer-review

Abstract

Studies of the glycosyltransferases (GTs) of small molecules have greatly increased in recent years as new approaches have been used to identify their genes and characterize their catalytic activities. These enzymes recognize diverse acceptors, including plant metabolites, phytotoxins and xenobiotics. Glycosylation alters the hydrophilicity of the acceptors, their stability and chemical properties, their subcellular localisation and often their bioactivity. Considerable progress has been made in understanding the role of GTs in the plant and the utility of GiTs as biocatalysts, the latter arising from their regio- and enantioselectivity and their ability to recognize substrates that are not limited to plant metabolites.

Original language	English
Pages (from-to)	254-263
Number of pages	10
Journal	CURRENT OPINION IN PLANT BIOLOGY
Volume	8
Issue number	3
DOIs	https://doi.org/10.1016/j.pbi.2005.03.007
Publication status	Published - Jun 2005

Keywords

CELL-SUSPENSION CULTURES
ARABIDOPSIS-THALIANA
UDP-GLUCOSE
PLANT GLYCOSYLTRANSFERASES
O-GLUCOSYLTRANSFERASE
SALICYLIC-ACID
BETANIDIN 5-O-GLUCOSYLTRANSFERASE
SUBSTRATE-SPECIFICITY
CATHARANTHUS-ROSEUS
MULTIGENE FAMILY

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10.1016/j.pbi.2005.03.007

Glucosyltransferases of the common phenylpropanoid pathway
Bowles, D. J.
BBSRC
1/10/04 → 30/09/07
Project: Research project (funded) › Research
Functional analysis of the glucosylation of auxin abscisic acid and their metabolites in Arabidopsis thaliana
Bowles, D. J.
BBSRC (BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL)
1/04/04 → 29/02/08
Project: Research project (funded) › Research

Cite this

@article{74287b21b0154c96905ca738dba76019,

title = "Glycosyltransferases: managers of small molecules",

abstract = "Studies of the glycosyltransferases (GTs) of small molecules have greatly increased in recent years as new approaches have been used to identify their genes and characterize their catalytic activities. These enzymes recognize diverse acceptors, including plant metabolites, phytotoxins and xenobiotics. Glycosylation alters the hydrophilicity of the acceptors, their stability and chemical properties, their subcellular localisation and often their bioactivity. Considerable progress has been made in understanding the role of GTs in the plant and the utility of GiTs as biocatalysts, the latter arising from their regio- and enantioselectivity and their ability to recognize substrates that are not limited to plant metabolites.",

keywords = "CELL-SUSPENSION CULTURES, ARABIDOPSIS-THALIANA, UDP-GLUCOSE, PLANT GLYCOSYLTRANSFERASES, O-GLUCOSYLTRANSFERASE, SALICYLIC-ACID, BETANIDIN 5-O-GLUCOSYLTRANSFERASE, SUBSTRATE-SPECIFICITY, CATHARANTHUS-ROSEUS, MULTIGENE FAMILY",

author = "D Bowles and J Isayenkova and Lim, {E K} and B Poppenberger",

year = "2005",

month = jun,

doi = "10.1016/j.pbi.2005.03.007",

language = "English",

volume = "8",

pages = "254--263",

journal = "CURRENT OPINION IN PLANT BIOLOGY",

issn = "1369-5266",

publisher = "Elsevier",

number = "3",

}

TY - JOUR

T1 - Glycosyltransferases: managers of small molecules

AU - Bowles, D

AU - Isayenkova, J

AU - Lim, E K

AU - Poppenberger, B

PY - 2005/6

Y1 - 2005/6

N2 - Studies of the glycosyltransferases (GTs) of small molecules have greatly increased in recent years as new approaches have been used to identify their genes and characterize their catalytic activities. These enzymes recognize diverse acceptors, including plant metabolites, phytotoxins and xenobiotics. Glycosylation alters the hydrophilicity of the acceptors, their stability and chemical properties, their subcellular localisation and often their bioactivity. Considerable progress has been made in understanding the role of GTs in the plant and the utility of GiTs as biocatalysts, the latter arising from their regio- and enantioselectivity and their ability to recognize substrates that are not limited to plant metabolites.

AB - Studies of the glycosyltransferases (GTs) of small molecules have greatly increased in recent years as new approaches have been used to identify their genes and characterize their catalytic activities. These enzymes recognize diverse acceptors, including plant metabolites, phytotoxins and xenobiotics. Glycosylation alters the hydrophilicity of the acceptors, their stability and chemical properties, their subcellular localisation and often their bioactivity. Considerable progress has been made in understanding the role of GTs in the plant and the utility of GiTs as biocatalysts, the latter arising from their regio- and enantioselectivity and their ability to recognize substrates that are not limited to plant metabolites.

KW - CELL-SUSPENSION CULTURES

KW - ARABIDOPSIS-THALIANA

KW - UDP-GLUCOSE

KW - PLANT GLYCOSYLTRANSFERASES

KW - O-GLUCOSYLTRANSFERASE

KW - SALICYLIC-ACID

KW - BETANIDIN 5-O-GLUCOSYLTRANSFERASE

KW - SUBSTRATE-SPECIFICITY

KW - CATHARANTHUS-ROSEUS

KW - MULTIGENE FAMILY

U2 - 10.1016/j.pbi.2005.03.007

DO - 10.1016/j.pbi.2005.03.007

M3 - Literature review

SN - 1369-5266

VL - 8

SP - 254

EP - 263

JO - CURRENT OPINION IN PLANT BIOLOGY

JF - CURRENT OPINION IN PLANT BIOLOGY

IS - 3

ER -

Glycosyltransferases: managers of small molecules

Abstract

Keywords

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Projects

Glucosyltransferases of the common phenylpropanoid pathway

Functional analysis of the glucosylation of auxin abscisic acid and their metabolites in Arabidopsis thaliana

Cite this