Green Solvent Selection for Emulsifiable Concentrate Agrochemical Formulations

Ana Pacheco, Thomas Attard, David Calvert, James Bullock, James H. Clark, James Sherwood*, C. Robert McElroy*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Emulsifiable concentrates are a common form of agrochemical formulation in which a high quantity of active ingredient is typically dissolved in an aromatic hydrocarbon solvent. There are considerable health and environmental hazards associated with the solvents in emulsifiable concentrates, and finding alternatives was deemed worthy of investigation. Using a combination of in silico modeling and experimental testing, a number of alternative safer solvents have been tested for the agrochemicals pendimethalin, prochloraz, and pyraclostrobin. Cyclohexanone, diethyl carbonate, ethyl acetate, and dihydrolevoglucosenone (Cyrene) were observed to be effective solvents.

Original languageEnglish
Number of pages5
JournalOrganic Process Research and Development
Early online date20 Dec 2023
Publication statusE-pub ahead of print - 20 Dec 2023

Bibliographical note

Publisher Copyright:
© 2023 The Authors. Published by American Chemical Society.


  • agrochemicals
  • formulations
  • modeling
  • solvents

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