Health-related quality of life outcome after on-pump versus off-pump coronary artery bypass graft surgery: A prospective randomized study

Reza Motallebzadeh; J. Martin Bland; Hugh S. Markus; Juan Carlos Kaski; Marjan Jahangiri

doi:10.1016/j.athoracsur.2006.03.081

Health-related quality of life outcome after on-pump versus off-pump coronary artery bypass graft surgery: A prospective randomized study

Reza Motallebzadeh, J. Martin Bland, Hugh S. Markus, Juan Carlos Kaski, Marjan Jahangiri

Health Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Background. The clinical benefit of off-pump coronary artery bypass graft surgery over on-pump surgery is a matter of controversy. The aim of this study was to assess quality of life in patients after on-pump and off-pump coronary artery bypass graft surgery, and compare the data with an age-matched and sex-matched standard population.

Methods. Two hundred twelve patients admitted for elective coronary artery bypass graft surgery were randomized to on-pump (n = 104) and off-pump (n = 108) surgery. Quality-of-life assessments were made 6 and 18 months postoperatively using the standard form of the Medical Outcomes Study 36-Item Short Form Health Survey (SF- 36, version 2). The questionnaire yields eight subscores of functional health and well being. The eight SF- 36 raw scores were standardized using means and standard deviations from a random sample of adults in Great Britain. Mean on-pump and off-pump SF- 36 scores were compared using two-sample Student's t tests.

Results. Questionnaires were completed for 72% (154 of 212) and 46% (98 of 212) of patients at the 6- and 18-month follow-up, respectively. There were no significant differences between on-pump and off-pump patients in any of the eight subscales at both stages. Fifty-six (72%) on-pump and 59 (75%) off-pump patients reported a better health status compared with the 6- month period before surgery (not significant).

Conclusions. Patients who have undergone off-pump coronary artery bypass graft surgery have a similar quality of life to on-pump patients at 6 and 18 months after surgery. For both groups, the majority of patients reported improved health after coronary artery bypass graft surgery compared with their preoperative status.

Original language	English
Pages (from-to)	615-619
Number of pages	5
Journal	The Annals of Thoracic Surgery
Volume	82
Issue number	2
DOIs	https://doi.org/10.1016/j.athoracsur.2006.03.081
Publication status	Published - Aug 2006

Keywords

NEUROCOGNITIVE FUNCTION
STATISTICS NOTES
MORTALITY
REGRESSION
MORBIDITY
TRIALS

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10.1016/j.athoracsur.2006.03.081

Cite this

@article{15ee3694c1c94650bd278ae892cb1f6f,

title = "Health-related quality of life outcome after on-pump versus off-pump coronary artery bypass graft surgery: A prospective randomized study",

abstract = "Background. The clinical benefit of off-pump coronary artery bypass graft surgery over on-pump surgery is a matter of controversy. The aim of this study was to assess quality of life in patients after on-pump and off-pump coronary artery bypass graft surgery, and compare the data with an age-matched and sex-matched standard population.Methods. Two hundred twelve patients admitted for elective coronary artery bypass graft surgery were randomized to on-pump (n = 104) and off-pump (n = 108) surgery. Quality-of-life assessments were made 6 and 18 months postoperatively using the standard form of the Medical Outcomes Study 36-Item Short Form Health Survey (SF- 36, version 2). The questionnaire yields eight subscores of functional health and well being. The eight SF- 36 raw scores were standardized using means and standard deviations from a random sample of adults in Great Britain. Mean on-pump and off-pump SF- 36 scores were compared using two-sample Student's t tests.Results. Questionnaires were completed for 72% (154 of 212) and 46% (98 of 212) of patients at the 6- and 18-month follow-up, respectively. There were no significant differences between on-pump and off-pump patients in any of the eight subscales at both stages. Fifty-six (72%) on-pump and 59 (75%) off-pump patients reported a better health status compared with the 6- month period before surgery (not significant).Conclusions. Patients who have undergone off-pump coronary artery bypass graft surgery have a similar quality of life to on-pump patients at 6 and 18 months after surgery. For both groups, the majority of patients reported improved health after coronary artery bypass graft surgery compared with their preoperative status.",

keywords = "NEUROCOGNITIVE FUNCTION, STATISTICS NOTES, MORTALITY, REGRESSION, MORBIDITY, TRIALS",

author = "Reza Motallebzadeh and Bland, {J. Martin} and Markus, {Hugh S.} and Kaski, {Juan Carlos} and Marjan Jahangiri",

year = "2006",

month = aug,

doi = "10.1016/j.athoracsur.2006.03.081",

language = "English",

volume = "82",

pages = "615--619",

journal = "The Annals of Thoracic Surgery",

issn = "0003-4975",

publisher = "Elsevier",

number = "2",

}

TY - JOUR

T1 - Health-related quality of life outcome after on-pump versus off-pump coronary artery bypass graft surgery: A prospective randomized study

AU - Motallebzadeh, Reza

AU - Bland, J. Martin

AU - Markus, Hugh S.

AU - Kaski, Juan Carlos

AU - Jahangiri, Marjan

PY - 2006/8

Y1 - 2006/8

N2 - Background. The clinical benefit of off-pump coronary artery bypass graft surgery over on-pump surgery is a matter of controversy. The aim of this study was to assess quality of life in patients after on-pump and off-pump coronary artery bypass graft surgery, and compare the data with an age-matched and sex-matched standard population.Methods. Two hundred twelve patients admitted for elective coronary artery bypass graft surgery were randomized to on-pump (n = 104) and off-pump (n = 108) surgery. Quality-of-life assessments were made 6 and 18 months postoperatively using the standard form of the Medical Outcomes Study 36-Item Short Form Health Survey (SF- 36, version 2). The questionnaire yields eight subscores of functional health and well being. The eight SF- 36 raw scores were standardized using means and standard deviations from a random sample of adults in Great Britain. Mean on-pump and off-pump SF- 36 scores were compared using two-sample Student's t tests.Results. Questionnaires were completed for 72% (154 of 212) and 46% (98 of 212) of patients at the 6- and 18-month follow-up, respectively. There were no significant differences between on-pump and off-pump patients in any of the eight subscales at both stages. Fifty-six (72%) on-pump and 59 (75%) off-pump patients reported a better health status compared with the 6- month period before surgery (not significant).Conclusions. Patients who have undergone off-pump coronary artery bypass graft surgery have a similar quality of life to on-pump patients at 6 and 18 months after surgery. For both groups, the majority of patients reported improved health after coronary artery bypass graft surgery compared with their preoperative status.

AB - Background. The clinical benefit of off-pump coronary artery bypass graft surgery over on-pump surgery is a matter of controversy. The aim of this study was to assess quality of life in patients after on-pump and off-pump coronary artery bypass graft surgery, and compare the data with an age-matched and sex-matched standard population.Methods. Two hundred twelve patients admitted for elective coronary artery bypass graft surgery were randomized to on-pump (n = 104) and off-pump (n = 108) surgery. Quality-of-life assessments were made 6 and 18 months postoperatively using the standard form of the Medical Outcomes Study 36-Item Short Form Health Survey (SF- 36, version 2). The questionnaire yields eight subscores of functional health and well being. The eight SF- 36 raw scores were standardized using means and standard deviations from a random sample of adults in Great Britain. Mean on-pump and off-pump SF- 36 scores were compared using two-sample Student's t tests.Results. Questionnaires were completed for 72% (154 of 212) and 46% (98 of 212) of patients at the 6- and 18-month follow-up, respectively. There were no significant differences between on-pump and off-pump patients in any of the eight subscales at both stages. Fifty-six (72%) on-pump and 59 (75%) off-pump patients reported a better health status compared with the 6- month period before surgery (not significant).Conclusions. Patients who have undergone off-pump coronary artery bypass graft surgery have a similar quality of life to on-pump patients at 6 and 18 months after surgery. For both groups, the majority of patients reported improved health after coronary artery bypass graft surgery compared with their preoperative status.

KW - NEUROCOGNITIVE FUNCTION

KW - STATISTICS NOTES

KW - MORTALITY

KW - REGRESSION

KW - MORBIDITY

KW - TRIALS

U2 - 10.1016/j.athoracsur.2006.03.081

DO - 10.1016/j.athoracsur.2006.03.081

M3 - Article

SN - 0003-4975

VL - 82

SP - 615

EP - 619

JO - The Annals of Thoracic Surgery

JF - The Annals of Thoracic Surgery

IS - 2

ER -