Heck reactions of amino acid building blocks: application to the synthesis of pyrrololine analogues

P N Collier, I Patel, R J K Taylor

Research output: Contribution to journalArticlepeer-review

Abstract

Heck reactions of unsaturated amino acid building blocks are described which allow acess to homo- and bis-homophenylalanine derivatives and to gamma,delta-unsaturated amino acids. Preliminary synthetic studies utilising this chemistry for the preparation of pyrrololine and deoxypyrrololine analogues are also reported. (C) 2002 Elsevier Science Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)3401-3405
Number of pages5
JournalTetrahedron Letters
Volume43
Issue number18
Publication statusPublished - 29 Apr 2002

Keywords

  • STEREOSELECTIVE SYNTHESIS
  • SIDE-CHAIN
  • DERIVATIVES
  • ELABORATION
  • COUPLINGS

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