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Hepatitis B vaccination induces mucosal antibody responses in the female genital tract, indicating potential mechanisms of protection against infection

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JournalSexually transmitted diseases
DateAccepted/In press - 12 Nov 2018
DateE-pub ahead of print (current) - 16 Nov 2018
Early online date16/11/18
Original languageEnglish

Abstract

Vaccines against hepatitis B virus confer effective protection. ELISA was developed to test for specific antibodies in female genital tract secretions. Anti-HBs IgG and IgA were detected in the cervico-vaginal secretions of women following Hepatitis B vaccination, indicating a potential genital tract role for neutralising antibodies against sexually transmitted HBV.

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© Copyright 2019 American Sexually Transmitted Diseases Association. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details.

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