By the same authors

From the same journal

Herpes simplex virus type 2 infection as a biomarker for sexual debut among young people in sub-Saharan Africa: a literature review

Research output: Contribution to journalArticle

Published copy (DOI)



Publication details

JournalInternational journal of STD & AIDS
DatePublished - 2012
Issue number11
Number of pages6
Pages (from-to)761-6
Original languageEnglish


Biological markers are needed in order to provide objective measures to validate self-reported sexual behaviour and interpret prevention trial data. In this review, we evaluated herpes simplex type 2 virus (HSV-2), one of the most prevalent sexually transmitted infections in sub-Saharan Africa as a biological marker of sexual debut. Based on our findings, we do not recommend using HSV-2 as a biomarker for sexual debut due to its low transmission probabilities and the fact that HSV-2 prevalence is not 100% among potential sexual partners. We recommend that the validation of alternative biological measures should be prioritized, and included in future studies and trials of interventions to reduce sexual health risk.

Discover related content

Find related publications, people, projects, datasets and more using interactive charts.

View graph of relations