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HERPES-SIMPLEX VIRUS TYPE-1 DNA-SEQUENCES ARE PRESENT IN AGED NORMAL AND ALZHEIMERS-DISEASE BRAIN BUT ABSENT IN LYMPHOCYTES

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JournalArchives of gerontology and geriatrics
DatePublished - 1992
Number of pages5
Pages (from-to)197-201
Original languageEnglish

Abstract

The etiology of Alzheimer's disease (AD) is unknown. Viruses have been suggested as a possible factor but the issue is still unresolved. We have detected herpes simplex virus type 1 DNA sequences in AD and normal brain, using polymerase chain reaction (PCR), and have now searched for the DNA in lymphocytes from AD patients and age-matched normal individuals; PCR shows that the virus is absent in the lymphocytes.

    Research areas

  • ALZHEIMERS DISEASE, HERPES SIMPLEX VIRUS TYPE-1, POLYMERASE CHAIN REACTION, LYMPHOCYTES, POLYMERASE CHAIN-REACTION, ENCEPHALITIS, DIAGNOSIS, TISSUE

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