Human O-GlcNAcase Uses a Preactivated Boat-like Substrate Conformation for Catalysis: Evidence from X-ray Crystallography and QM/MM Metadynamics

Martín Calvelo, Alexandra Males, Matthew G. Alteen, Lianne I. Willems, David J. Vocadlo, Gideon J. Davies, Carme Rovira

Chemistry

Research output: Contribution to journal › Article › peer-review

1 Finished
2 Active

3 results

Active

CARBOCENTRE: Activity-Based Profiling of Glycoprocessing Enzymes for Human Health and a Sustainable Society
Davies, G. J. (Principal investigator)
EUROPEAN COMMISSION
1/06/21 → 31/05/27
Project: Research project (funded) › Research
RS Research Professorship
Davies, G. J. (Principal investigator)
THE ROYAL SOCIETY
1/01/17 → 31/12/26
Project: Research project (funded) › Research
Finished

Dissection of the Leishmania mannogen biosynthetic pathway: beta 1-2 mannan in pathogens and beyond
Davies, G. J. (Principal investigator)
BBSRC (BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL)
20/01/20 → 19/04/23
Project: Research project (funded) › Research