The York Research Database

Water networks can determine the affinity of ligand binding to proteins

Darby, J. F., Hopkins, A., Hubbard, R. E., Roberts, S. M., Shimizu, S., Brannigan, J. A., Turkenburg, J., Thomas, G. H. & Fischer, M., 13 Sep 2019

Article in Journal of the American Chemical Society

1D NMR WaterLOGSY as an efficient method for fragment-based lead discovery

Raingeval, C., Cala, O., Brion, B., Le Borgne, M., Hubbard, R. E. & Krimm, I., 9 Jul 2019

Article in JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1

Murray, J. B., Davidson, J., Chen, I., Davis, B., Dokurno, P., Graham, C. J., Harris, R., Jordan, A., Matassova, N., Pedder, C., Ray, S., Roughley, S. D., Smith, J., Walmsley, C., Wang, Y., Whitehead, N., Williamson, D. S., Casara, P., Le Diguarher, T., Hickman, J. & 4 others, Stark, J., Kotschy, A., Geneste, O. & Hubbard, R. E., 23 May 2019

Article in ACS Omega

Predicting how drug molecules bind to their protein targets

Rachman, M. M., Barril, X. & Hubbard, R. E., 1 Oct 2018

Review article in Current Opinion in Pharmacology

Using fragment-based approaches to discover new antibiotics

Hubbard, R. E. & Lamoree, B., 1 Jul 2018

Article in SLAS Discovery

Density modification for macromolecular phase improvement

Cowtan, K. D. & Zhang, K. Y. J., 1999

Literature review in PROGRESS IN BIOPHYSICS

A framework for the analysis of mixed time series/point process data-Theory and application to the study of physiological tremor, single motor unit discharges and electromyograms

Halliday, D. M., Rosenberg, J. R., Amjad, A. M., Breeze, P., Conway, B. A. & Farmer, S. F., 1995

Article in Progress in Biophysics & Molecular Biology

The Fourier approach to the identification of functional coupling between neuronal spike trains

Rosenberg, J. R., Amjad, A. M., Breeze, P., Brillinger, D. R. & Halliday, D. M., 1989

Article in Progress in Biophysics & Molecular Biology