Abstract
Individual participant data (IPD) reviews are a specific type of systematic review that involve the collection, checking and re-analysis of the original data for each participant in each study. This chapter provides an overview of the IPD approach to systematic reviews, to help authors decide whether collecting IPD might be useful and feasible for their review. Just as for other types of systematic review, assessing risk of bias of included studies is recommended for IPD reviews. With the collaborative IPD approach, additional information obtained from protocols, codebooks and forms supplied by study investigators can increase the clarity of risk of bias assessments compared to those based on study reports. As IPD offers the potential to analyse data in many different ways, it is particularly important that all methods relating to analysis are pre-specified in detail in the review protocol or analysis plan and are clearly reported in publications.
| Original language | English |
|---|---|
| Title of host publication | Cochrane Handbook for Systematic Reviews of Interventions |
| Publisher | Wiley-Blackwell |
| Chapter | 26 |
| Pages | 643-658 |
| Number of pages | 16 |
| ISBN (Electronic) | 9781119536604 |
| ISBN (Print) | 9781119536628 |
| DOIs | |
| Publication status | Published - 20 Sept 2019 |
Keywords
- Analysis plan
- Collaborative IPD approach
- Individual participant data
- Review authors
- Review protocol
- Risk of bias assessments
- Study reports
- Systematic review