Infections

Silvia Franceschi, Rolando Herrero, Andrew J. Hall (Editor), Robert Newton (Editor), You-Lin Qiao (Editor)

Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

Abstract

• Infections with viruses, bacteria, and macroparasites have been identified as strong risk factors for specific cancers.
• Overall, about 2 million (16%) of the total of 12.7 million new cancer cases in 2008 are attributable to infections. This fraction varies 10-fold by region; it is lowest in North America, Australia, and New Zealand (≤ 4%) and highest in sub-Saharan Africa (33%).
• Helicobacter pylori, hepatitis B and C viruses, and human papillomaviruses are responsible for 1.9 million cancer cases globally, including mainly gastric, liver, and cervical cancer, respectively.
• Infection with HIV substantially increases the risk of virusassociated cancers, through immunosuppression.
• Application of existing methods for infection prevention, such as vaccination, safe injection practices, and safe sexual behaviour, or antimicrobial and antiparasite treatments could have a major impact on the future burden of
cancer worldwide.
Original languageEnglish
Title of host publicationWorld Cancer Report 2014
EditorsB. V. Stewart, C. P. Wild
Place of PublicationLyons
PublisherInternational Agency for Research on Cancer
Chapter2.4
Pages105-114
Number of pages10
Volume2014
ISBN (Print)978-92-832-0443-5
Publication statusPublished - 2014

Publication series

NameWorld Cancer Report
PublisherInternational Agency for Resarech on Cancer

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