Abstract
• Infections with viruses, bacteria, and macroparasites have been identified as strong risk factors for specific cancers.
• Overall, about 2 million (16%) of the total of 12.7 million new cancer cases in 2008 are attributable to infections. This fraction varies 10-fold by region; it is lowest in North America, Australia, and New Zealand (≤ 4%) and highest in sub-Saharan Africa (33%).
• Helicobacter pylori, hepatitis B and C viruses, and human papillomaviruses are responsible for 1.9 million cancer cases globally, including mainly gastric, liver, and cervical cancer, respectively.
• Infection with HIV substantially increases the risk of virusassociated cancers, through immunosuppression.
• Application of existing methods for infection prevention, such as vaccination, safe injection practices, and safe sexual behaviour, or antimicrobial and antiparasite treatments could have a major impact on the future burden of
cancer worldwide.
• Overall, about 2 million (16%) of the total of 12.7 million new cancer cases in 2008 are attributable to infections. This fraction varies 10-fold by region; it is lowest in North America, Australia, and New Zealand (≤ 4%) and highest in sub-Saharan Africa (33%).
• Helicobacter pylori, hepatitis B and C viruses, and human papillomaviruses are responsible for 1.9 million cancer cases globally, including mainly gastric, liver, and cervical cancer, respectively.
• Infection with HIV substantially increases the risk of virusassociated cancers, through immunosuppression.
• Application of existing methods for infection prevention, such as vaccination, safe injection practices, and safe sexual behaviour, or antimicrobial and antiparasite treatments could have a major impact on the future burden of
cancer worldwide.
Original language | English |
---|---|
Title of host publication | World Cancer Report 2014 |
Editors | B. V. Stewart, C. P. Wild |
Place of Publication | Lyons |
Publisher | International Agency for Research on Cancer |
Chapter | 2.4 |
Pages | 105-114 |
Number of pages | 10 |
Volume | 2014 |
ISBN (Print) | 978-92-832-0443-5 |
Publication status | Published - 2014 |
Publication series
Name | World Cancer Report |
---|---|
Publisher | International Agency for Resarech on Cancer |