By the same authors

From the same journal

Innovations in the psychopathology of schizophrenia: A primer for busy clinicians

Research output: Contribution to journalArticlepeer-review



Publication details

JournalBJPsych Advances
DatePublished - 16 Mar 2022
Issue number2
Number of pages11
Pages (from-to)79-89
Original languageEnglish


Significant developments in schizophrenia psychopathology are ready to be incorporated into clinical practice. These advances allow a way forward through the well-described challenges experienced with current diagnostic and psychopathological frameworks. This article discusses approaches that will enable clinicians to access a wider and richer spectrum of patient experience; describes process-based models of schizophrenia in the domains of both the brain and the mind; and considers how different levels of analysis might be linked via the predictive processing framework. Multiple levels of analysis provide different targets for varying modalities of treatment - dopamine blockade at the molecular level, psychological therapy at the level of the mind, and social interventions at the personal level. Psychiatry needs to align itself closer to neuroscientific research. It should move from a symptom-based understanding to a model based on process. That is - after having asked about a patient's symptoms and experience clinicians need to introduce steps involving a consideration of what might be the brain and mind processes underlying the experience.

Bibliographical note

Funding Information:
This research received no specific grant from any funding agency, commercial or not-for-profit sectors.

Publisher Copyright:
Copyright © The Author(s) 2021. Published by Cambridge University Press on behalf of the Royal College of Psychiatrists.

    Research areas

  • neuroscience, phenomenology, predictive processing, psychopathology, Schizophrenia

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