Introducing an amine group to calix[5]arene: Comparison of several methods

TY - JOUR

T1 - Introducing an amine group to calix[5]arene

T2 - Comparison of several methods

AU - Kundrat, Ondrej

AU - Slavik, Petr

AU - Miksatko, Jiri

PY - 2016/6/2

Y1 - 2016/6/2

N2 - Chemists often use an amine group as an intermediate in syntheses of imines, amides and ureas; however, in the case of syntheses of p-aminophenol type compounds, several problems might occur. In this article, we prepared p-aminocalix[5]arene-pentaol by reduction of both nitro and azo derivatives, and compared four methods of the amine preparation, focusing mainly on its gramme scale and time-consuming issues.

AB - Chemists often use an amine group as an intermediate in syntheses of imines, amides and ureas; however, in the case of syntheses of p-aminophenol type compounds, several problems might occur. In this article, we prepared p-aminocalix[5]arene-pentaol by reduction of both nitro and azo derivatives, and compared four methods of the amine preparation, focusing mainly on its gramme scale and time-consuming issues.

KW - amine

KW - azo coupling

KW - Calixarene

KW - nitration

UR - http://www.scopus.com/inward/record.url?scp=84949555547&partnerID=8YFLogxK

U2 - 10.1080/10610278.2015.1119275

DO - 10.1080/10610278.2015.1119275

M3 - Article

AN - SCOPUS:84949555547

SN - 1061-0278

VL - 28

SP - 450

EP - 454

JO - Supramolecular Chemistry

JF - Supramolecular Chemistry

IS - 5-6

ER -