A method of urothelial cell sheet formation with subsequent combination with polyglactin mesh to provide a transplant vehicle for the efficient transfer of cultured urothelial cells to a stromal base was proposed. The urothelial cell sheet:polyglactin complex recombination with a stromal base, produced a stratified epithelium incorporating the biodegradable mesh fibres. The resultant stroma:mesh:urothelium combination was analyzed by histological and immunohistochemical techniques. The immunohistochemcial analysis showed that the cells has retained their transitional phenotype following transplantation.
|Number of pages||1|
|Publication status||Published - 2000|
|Event||Second Smith and Nephew International Symposium - Tissue Engineering 2000: Advances in Tissue Engineering, Biomaterials and Cell Signalling - York, United Kingdom|
Duration: 16 Jul 2000 → 19 Jul 2000
|Conference||Second Smith and Nephew International Symposium - Tissue Engineering 2000: Advances in Tissue Engineering, Biomaterials and Cell Signalling|
|Period||16/07/00 → 19/07/00|