Investigation of biodegradable scaffolds suitable for urothelial cell transplantation

TY - CONF

T1 - Investigation of biodegradable scaffolds suitable for urothelial cell transplantation

AU - Scriven, S. D.

AU - Trejdosiewicz, L. K.

AU - Thomas, D. F.M.

AU - Southgate, J.

PY - 2000

Y1 - 2000

N2 - A method of urothelial cell sheet formation with subsequent combination with polyglactin mesh to provide a transplant vehicle for the efficient transfer of cultured urothelial cells to a stromal base was proposed. The urothelial cell sheet:polyglactin complex recombination with a stromal base, produced a stratified epithelium incorporating the biodegradable mesh fibres. The resultant stroma:mesh:urothelium combination was analyzed by histological and immunohistochemical techniques. The immunohistochemcial analysis showed that the cells has retained their transitional phenotype following transplantation.

AB - A method of urothelial cell sheet formation with subsequent combination with polyglactin mesh to provide a transplant vehicle for the efficient transfer of cultured urothelial cells to a stromal base was proposed. The urothelial cell sheet:polyglactin complex recombination with a stromal base, produced a stratified epithelium incorporating the biodegradable mesh fibres. The resultant stroma:mesh:urothelium combination was analyzed by histological and immunohistochemical techniques. The immunohistochemcial analysis showed that the cells has retained their transitional phenotype following transplantation.

UR - http://www.scopus.com/inward/record.url?scp=18644376193&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:18644376193

SP - 28

T2 - Second Smith and Nephew International Symposium - Tissue Engineering 2000: Advances in Tissue Engineering, Biomaterials and Cell Signalling

Y2 - 16 July 2000 through 19 July 2000

ER -