Investigation of bispidines as the stoichiometric ligand in the two-ligand catalytic asymmetric deprotonation of N-Boc pyrrolidine

Graeme Barker*, Peter O'Brien, Kevin R. Campos

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

A range of achiral bispidines have been synthesized and evaluated as the stoichiometric ligand in the two-ligand catalytic asymmetric deprotonation of N-Boc pyrrolidine.

Original languageEnglish
Pages (from-to)217-229
Number of pages13
JournalARKIVOC
Volume2011
Issue number5
Publication statusPublished - 3 Apr 2011

Keywords

  • (-)-sparteine
  • Asymmetric synthesis
  • Nitrogen heterocycles
  • Organolithium reagents

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