Is trehalose-6-phosphate a regulator of sugar metabolism in plants?

TY - JOUR

T1 - Is trehalose-6-phosphate a regulator of sugar metabolism in plants?

AU - Eastmond, P J

AU - Li, Y

AU - Graham, I A

PY - 2003/1

Y1 - 2003/1

N2 - It has recently emerged that many higher plants can synthesize trace amounts of trehalose. In arabidopsis disruption of the first step of trehalose synthesis, catalysed by trehalose-6-phosphate synthase (TPS), has lethal consequences, demonstrating an important physiological role. It is not yet clear what the precise function of trehalose synthesis is, but there is mounting evidence that trehalose-6-phosphate is implicated in the regulation of sugar metabolism. Further work is necessary to confirm this hypothesis and determine the underlying mechanism.

AB - It has recently emerged that many higher plants can synthesize trace amounts of trehalose. In arabidopsis disruption of the first step of trehalose synthesis, catalysed by trehalose-6-phosphate synthase (TPS), has lethal consequences, demonstrating an important physiological role. It is not yet clear what the precise function of trehalose synthesis is, but there is mounting evidence that trehalose-6-phosphate is implicated in the regulation of sugar metabolism. Further work is necessary to confirm this hypothesis and determine the underlying mechanism.

KW - Arabidopsis

KW - trehalose

KW - trehalose-6-phosphate

KW - trehalose-6-phosphate synthase

KW - SACCHAROMYCES-CEREVISIAE

KW - TREHALOSE BIOSYNTHESIS

KW - ARABIDOPSIS-THALIANA

KW - TPS1 MUTANT

KW - SYNTHASE

KW - YEAST

KW - GLYCOLYSIS

KW - HEXOKINASE

KW - GENE

KW - FERMENTATION

U2 - 10.1093/jxb/erg039

DO - 10.1093/jxb/erg039

M3 - Article

SN - 0022-0957

VL - 54

SP - 533

EP - 537

JO - Journal of Experimental Botany

JF - Journal of Experimental Botany

IS - 382

ER -