Activities per year
Abstract
The occipital lobe contains retinotopic representations of the visual field. The representation of the central retina in early visual areas (V1-3) is found at the occipital pole. When the central retina is lesioned in both eyes by macular degeneration, this region of visual cortex at the occipital pole is accordingly deprived of input. However, even when such lesions occur in adulthood, some visually driven activity in and around the occipital pole can be observed. It has been suggested that this activity is a result of remapping of this area so that it now responds to inputs from intact, peripheral retina. We evaluated whether or not remapping of visual cortex underlies this activity. Our functional magnetic resonance imaging results provide no evidence of remapping, questioning the contemporary view that early visual areas of the adult human brain have the capacity to reorganize extensively.
Original language | English |
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Pages (from-to) | 649-655 |
Number of pages | 7 |
Journal | Nature neuroscience |
Volume | 14 |
Issue number | 5 |
DOIs | |
Publication status | Published - May 2011 |
Keywords
- Adult
- Age Factors
- Aged
- Aged, 80 and over
- Analysis of Variance
- Brain Mapping
- Computer Simulation
- Female
- Humans
- Image Processing, Computer-Assisted
- Macular Degeneration
- Magnetic Resonance Imaging
- Male
- Middle Aged
- Oxygen
- Photic Stimulation
- Probability
- Visual Cortex
- Visual Fields
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Plasticity and stability in human foveal pathways
Baseler, H. (Invited speaker)
4 Oct 2024Activity: Talk or presentation › Symposium
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The effects of macular degeneration on the eye, brain and behaviour
Heidi Baseler (Invited speaker)
1 Jun 2023Activity: Talk or presentation › Invited talk
Projects
- 1 Finished
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Topography of the cortical representation of ...
MEDICAL RESEARCH COUNCIL (MRC)
1/01/06 → 30/09/09
Project: Research project (funded) › Research