Learning to unwind

Research output: Contribution to journalEditorialpeer-review

Abstract

DNA helicases unwind DNA by a number of mechanisms in which conformational change seems to be of central importance. Characterization of two beta-hairpins and fluorescence resonance energy transfer studies of protein-DNA interactions in the minichromosome maintenance proteins afford new insights into the molecular mechanisms of these proteins.

Original languageEnglish
Pages (from-to)734-736
Number of pages3
JournalNature structural & molecular biology
Volume12
Issue number9
DOIs
Publication statusPublished - Sept 2005

Keywords

  • MINICHROMOSOME MAINTENANCE PROTEIN
  • DNA HELICASE ACTIVITY
  • LARGE TUMOR-ANTIGEN
  • THERMOAUTOTROPHICUM
  • REPLICATION
  • MECHANISM
  • COMPLEX
  • MCM
  • ATPASES
  • DOMAIN

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