Projects per year
DNA helicases unwind DNA by a number of mechanisms in which conformational change seems to be of central importance. Characterization of two beta-hairpins and fluorescence resonance energy transfer studies of protein-DNA interactions in the minichromosome maintenance proteins afford new insights into the molecular mechanisms of these proteins.
- MINICHROMOSOME MAINTENANCE PROTEIN
- DNA HELICASE ACTIVITY
- LARGE TUMOR-ANTIGEN