Low temperature plasma causes double-strand break DNA damage in primary epithelial cells cultured from a human prostate Tumor

TY - JOUR

T1 - Low temperature plasma causes double-strand break DNA damage in primary epithelial cells cultured from a human prostate Tumor

AU - Hirst, Adam M.

AU - Frame, Fiona M.

AU - Maitland, Norman J.

AU - O'Connell, Deborah

PY - 2014/10/1

Y1 - 2014/10/1

N2 - Research in the new field of plasma medicine continues to demonstrate the efficacy of low temperature plasmas (LTPs) for numerous biomedical applications. Responses such as reduction in cell viability and cell death for cancer therapy, cell proliferation for wound healing, and bacterial inactivation have been observed as a result of plasma treatment. In this paper, we applied LTP to prostate cancer primary cells derived from patient tumour tissue to inflict irreparable DNA damage.

AB - Research in the new field of plasma medicine continues to demonstrate the efficacy of low temperature plasmas (LTPs) for numerous biomedical applications. Responses such as reduction in cell viability and cell death for cancer therapy, cell proliferation for wound healing, and bacterial inactivation have been observed as a result of plasma treatment. In this paper, we applied LTP to prostate cancer primary cells derived from patient tumour tissue to inflict irreparable DNA damage.

KW - Atmospheric pressure plasma

KW - cells (biology)

KW - DNA

KW - oncology

UR - http://www.scopus.com/inward/record.url?scp=84908454597&partnerID=8YFLogxK

U2 - 10.1109/TPS.2014.2351453

DO - 10.1109/TPS.2014.2351453

M3 - Article

AN - SCOPUS:84908454597

SN - 0093-3813

VL - 42

SP - 2740

EP - 2741

JO - IEEE transactions on plasma science

JF - IEEE transactions on plasma science

IS - 10

M1 - 6894576

ER -