Mathematical Virology: A mathematical physicist's approach to the protein stoichiometry and bonding structure of viral capsids

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Publication details

Title of host publicationGroup Theoretical Methods in Physics
DatePublished - 2005
Pages113-120
Number of pages8
PublisherIOP PUBLISHING LTD
EditorsG.S. Pogosyan, L.E. Vincent, K.B. Wolf
Volume185
Original languageEnglish
ISBN (Print)0-7503-1008-1

Publication series

NameConference Series
PublisherInstitute of Physics
Number185

Abstract

An important constituent of a virus is its capsid, that is a shell formed from proteins that encapsulates the viral genome. The capsids of a large number of viruses have overall icosahedral symmetry, which suggests the use of group theoretical methods for their description. Viral Tiling Theory combines group theory with tiling theory in order to model the surface structures of viral capsids and their tubular variants. It predicts the locations of the protein subunits and the inter-subunit bonds in the capsids and forms a basis for the construction of assembly models.

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