Mathematical Virology: A mathematical physicist's approach to the protein stoichiometry and bonding structure of viral capsids

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

An important constituent of a virus is its capsid, that is a shell formed from proteins that encapsulates the viral genome. The capsids of a large number of viruses have overall icosahedral symmetry, which suggests the use of group theoretical methods for their description. Viral Tiling Theory combines group theory with tiling theory in order to model the surface structures of viral capsids and their tubular variants. It predicts the locations of the protein subunits and the inter-subunit bonds in the capsids and forms a basis for the construction of assembly models.
Original languageEnglish
Title of host publicationGroup Theoretical Methods in Physics
Subtitle of host publicationProceedings of the XXV International Colloquium on Group Theoretical Methods in Physics, Cocoyoc, Mexico, 2-6 August 2004
EditorsG.S. Pogosyan, L.E. Vincent, K.B. Wolf
PublisherIOP Publishing
Pages113-120
Number of pages8
Volume185
ISBN (Print)0-7503-1008-1
Publication statusPublished - 2005

Publication series

NameConference Series
PublisherInstitute of Physics
Number185

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