Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations

Stephan Wilmes; Maximillian  Hafer; Joni  Vuorio; Julie Ann Tucker; Hauke  Winkelmann; Sara Lochte; Tess Archana Stanly; Katiuska D Pulgar Prieto; Chetan  Poojari; Vivek  Sharma; Christian P Richter; Rainer  Kurre; Stevan R Hubbard; K Christopher  Garcia; Ignacio  Moraga; Ilpo  Vattulainen; Ian Stuart Hitchcock; Jacob Piehler

doi:10.1126/science.aaw3242

Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations

Stephan Wilmes, Maximillian Hafer, Joni Vuorio, Julie Ann Tucker, Hauke Winkelmann, Sara Lochte, Tess Archana Stanly, Katiuska D Pulgar Prieto, Chetan Poojari, Vivek Sharma, Christian P Richter, Rainer Kurre, Stevan R Hubbard, K Christopher Garcia, Ignacio Moraga, Ilpo Vattulainen, Ian Stuart Hitchcock, Jacob Piehler

Biology

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	643-652
Number of pages	10
Journal	Science
Volume	367
Issue number	6478
Early online date	7 Feb 2020
DOIs	https://doi.org/10.1126/science.aaw3242
Publication status	E-pub ahead of print - 7 Feb 2020

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© 2020 The Authors. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details.

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10.1126/science.aaw3242

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© 2020 The Authors. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details.
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Ian Stuart Hitchcock
- ian.hitchcockyork.acuk
- Biology - Professor
Person: Academic

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Wilmes, S., Hafer, M., Vuorio, J., Tucker, J. A., Winkelmann, H., Lochte, S., Stanly, T. A., Pulgar Prieto, K. D., Poojari, C., Sharma, V., Richter, C. P., Kurre, R., Hubbard, S. R., Garcia, K. C., Moraga, I., Vattulainen, I., Hitchcock, I. S., & Piehler, J. (2020). Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations. Science, 367(6478), 643-652. Advance online publication. https://doi.org/10.1126/science.aaw3242

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title = "Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations",

author = "Stephan Wilmes and Maximillian Hafer and Joni Vuorio and Tucker, {Julie Ann} and Hauke Winkelmann and Sara Lochte and Stanly, {Tess Archana} and {Pulgar Prieto}, {Katiuska D} and Chetan Poojari and Vivek Sharma and Richter, {Christian P} and Rainer Kurre and Hubbard, {Stevan R} and Garcia, {K Christopher} and Ignacio Moraga and Ilpo Vattulainen and Hitchcock, {Ian Stuart} and Jacob Piehler",

note = " {\textcopyright} 2020 The Authors. This is an author-produced version of the published paper. Uploaded in accordance with the publisher{\textquoteright}s self-archiving policy. Further copying may not be permitted; contact the publisher for details. ",

year = "2020",

month = feb,

day = "7",

doi = "10.1126/science.aaw3242",

language = "English",

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Wilmes, S, Hafer, M, Vuorio, J, Tucker, JA, Winkelmann, H, Lochte, S, Stanly, TA, Pulgar Prieto, KD, Poojari, C, Sharma, V, Richter, CP, Kurre, R, Hubbard, SR, Garcia, KC, Moraga, I, Vattulainen, I, Hitchcock, IS & Piehler, J 2020, 'Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations', Science, vol. 367, no. 6478, pp. 643-652. https://doi.org/10.1126/science.aaw3242

TY - JOUR

T1 - Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations

AU - Wilmes, Stephan

AU - Hafer, Maximillian

AU - Vuorio, Joni

AU - Tucker, Julie Ann

AU - Winkelmann, Hauke

AU - Lochte, Sara

AU - Stanly, Tess Archana

AU - Pulgar Prieto, Katiuska D

AU - Poojari, Chetan

AU - Sharma, Vivek

AU - Richter, Christian P

AU - Kurre, Rainer

AU - Hubbard, Stevan R

AU - Garcia, K Christopher

AU - Moraga, Ignacio

AU - Vattulainen, Ilpo

AU - Hitchcock, Ian Stuart

AU - Piehler, Jacob

N1 - © 2020 The Authors. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details.

PY - 2020/2/7

Y1 - 2020/2/7

U2 - 10.1126/science.aaw3242

DO - 10.1126/science.aaw3242

M3 - Article

SN - 0036-8075

VL - 367

SP - 643

EP - 652

JO - Science

JF - Science

IS - 6478

ER -

Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations

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