Mechanistic Insight into Enzymatic Glycosyl Transfer with Retention of Configuration through Analysis of Glycomimetic Inhibitors

James C. Errey, Seung Seo Lee, Robert P. Gibson, Carlos Martinez Fleites, Conor S. Barry, Pierre M. J. Jung, Anthony C. O'Sullivan, Benjamin G. Davis, Gideon J. Davies

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)1234-1237
Number of pages4
JournalAngewandte Chemie International Edition
Volume49
Issue number7
DOIs
Publication statusPublished - 8 Feb 2010

Keywords

  • bisubstrate mimetic
  • enzymes
  • glycosyltransferases
  • internal return
  • trehaloses
  • ANTIBIOTIC VALIDAMYCINS
  • CRYSTAL-STRUCTURE
  • GLYCOSYLTRANSFERASES
  • TREHALOSE
  • COMPLEX
  • DONOR
  • BIOSYNTHESIS
  • INTERMEDIATE
  • SOLVOLYSIS
  • ANALOGS

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