Mechanistic Insights into the Chaperoning of Human Lysosomal-Galactosidase Activity: Highly Functionalized Aminocyclopentanes and C-5a-Substituted Derivatives of 4-epi-Isofagomine

Patrick Weber, Martin Thonhofer, Summer Averill, Gideon J. Davies, Andres Gonzalez Santana, Philipp Müller, Seyed A. Nasseri, Wendy A. Offen, Bettina M. Pabst, Eduard Paschke, Michael Schalli, Ana Torvisco, Marion Tschernutter, Christina Tysoe, Werner Windischhofer, Stephen G. Withers, Andreas Wolfsgruber, Tanja M. Wrodnigg, Arnold E. Stütz^*

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

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RS Research Professorship
DAVIES, G. (Principal investigator)
THE ROYAL SOCIETY
1/01/17 → 31/12/26
Project: Research project (funded) › Research
Finished

Application of activity-based glycosidase probes for mechanism, enzyme discovery and clinical diagnosis
DAVIES, G. (Principal investigator)
BBSRC (BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL)
1/01/18 → 31/12/21
Project: Research project (funded) › Research

Mechanistic Insights into the Chaperoning of Human Lysosomal-Galactosidase Activity: Highly Functionalized Aminocyclopentanes and C-5a-Substituted Derivatives of 4-epi-Isofagomine

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RS Research Professorship

Finished

Application of activity-based glycosidase probes for mechanism, enzyme discovery and clinical diagnosis