Meta-arylation of calixarenes using organomercurial chemistry

Petr Slavík, Karolína Flídrová, Hana Dvořáková, Václav Eigner, Pavel Lhoták*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


A direct mercuration reaction combined with a subsequent Pd-catalyzed arylation was used to introduce the aryl moiety into the meta position of the calix[4]arene skeleton. The application of organomercurial intermediates thus allows the straightforward formation of meta-aryl-substituted derivatives representing a unique substitution pattern in calixarene chemistry.

Original languageEnglish
Pages (from-to)5528-5534
Number of pages7
JournalOrganic and Biomolecular Chemistry
Issue number33
Publication statusPublished - 1 Jan 2013

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